Full Text
The Full Text of this article is available as a PDF (237.0 KB).
Figure 1 .

Carpentier and Duran nomenclatures of the mitral valve. In the Duran nomenclature, the three scallops of the posterior leaflet are named P1, PM (middle), and P2. The anterior leaflet has only two scallops A1 and A2. The Carpentier nomenclature is described in the text. AV, aortic valve; PV, pulmonic valve; TV, tricuspid valve.
Figure 2 .
Cross sectional drawing of the heart at the level of the atrioventricular valves. Dotted lines show the planes of the different views obtained during TOE or TTE studies. Left atrial appendage and aortic valve are the landmarks that must be seen or not on the image according to the view. For example, the four chamber view excludes the left ventricular outflow tract and the aortic valve. Figure 2 and table 1 are closely related. AV, aortic valve; LAA, left atrial appendage; LAX, long axis view; PLAX, parasternal long axis view; PV, pulmonic valve, TOE, transoesophageal echo; TTE, transthoracic echo.
Figure 3 .
Left panel: transthoracic apical four chamber view in a patient with P2 prolapse. Although A3-A2-P1 scallops are usually seen in this view, the P2 scallop prolapse is seen behind A2. Right panel: transoesophageal four chamber view 40–50° showing the same scallops as the transthoracic four chamber view in a normal subject. TOE, transoesophageal echo; TTE, transthoracic echo.
Figure 4 .
Transthoracic apical four chamber view in a patient with P2 prolapse. Left panel: on the grey scale image, the P2 scallop is visualised behind A2. Right panel: using colour Doppler flow in the same patient, there is an oblique jet of mitral regurgitation going behind the anterior leaflet which hugs the interatrial septum.
Figure 5 .
Left panel: transthoracic apical two chamber view in a patient with P2 prolapse. P2 scallop is visualised behind A2. Right panel: transoesophageal intercommissural two chamber view 75–90° showing the same scallops as the transthoracic view in another patient with A2 prolapse. LAA, left atrial appendage.
Figure 6 .
Left panel: transthoracic parasternal long axis (PLAX) view in a patient with P2 prolapse. In that view, the aortic valve and the ascending aorta must be well defined. Right panel: transoesophageal long axis (LAX) view 120–140° in the same patient.
Figure 7 .
Transoesophageal long axis view 120–140° in the same patient as in fig 6 with colour Doppler flow showing an oblique jet of mitral regurgitation behind the anterior leaflet.
Figure 8 .
Left panel: transthoracic parasternal short axis (SAX) view at the level of the mitral valve showing the six scallops of the Carpentier nomenclature in a normal subject. Right panel: transoesophageal transgastric view 0° showing the mitral valve scallops in a normal subject.
Figure 9 .
Transthoracic parasternal short axis view at the level of the mitral valve in a 45 year old man undergoing chronic haemodialysis. Massive calcifications of the mitral annulus are seen, mainly in the posterior region. Mitral annular calcification is recognised as a bulky echodensity adjacent to the bases of the mitral leaflets. Calcifications can extend into the bases of the leaflets and restrict their motion. Acoustic shadowing of the left atrium in the presence of mitral annular calcification may impede the detection of mitral regurgitation on transthoracic echocardiography.
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Barlow J. B., Pocock W. A. Billowing, floppy, prolapsed or flail mitral valves? Am J Cardiol. 1985 Feb 1;55(4):501–502. doi: 10.1016/0002-9149(85)90402-3. [DOI] [PubMed] [Google Scholar]
- Barlow J. B., Pocock W. A., Obel I. W. Mitral valve prolapse: primary, secondary, both or neither? Am Heart J. 1981 Jul;102(1):140–143. doi: 10.1016/0002-8703(81)90435-x. [DOI] [PubMed] [Google Scholar]
- Carpentier A. F., Lessana A., Relland J. Y., Belli E., Mihaileanu S., Berrebi A. J., Palsky E., Loulmet D. F. The "physio-ring": an advanced concept in mitral valve annuloplasty. Ann Thorac Surg. 1995 Nov;60(5):1177–1186. doi: 10.1016/0003-4975(95)00753-8. [DOI] [PubMed] [Google Scholar]
- Carpentier A., Chauvaud S., Fabiani J. N., Deloche A., Relland J., Lessana A., D'Allaines C., Blondeau P., Piwnica A., Dubost C. Reconstructive surgery of mitral valve incompetence: ten-year appraisal. J Thorac Cardiovasc Surg. 1980 Mar;79(3):338–348. [PubMed] [Google Scholar]
- Carpentier A., Deloche A., Dauptain J., Soyer R., Blondeau P., Piwnica A., Dubost C., McGoon D. C. A new reconstructive operation for correction of mitral and tricuspid insufficiency. J Thorac Cardiovasc Surg. 1971 Jan;61(1):1–13. [PubMed] [Google Scholar]
- Cohen I. S. Two-dimensional echocardiographic mitral valve prolapse: evidence for a relationship of echocardiographic morphology to clinical findings and to mitral annular size. Am Heart J. 1987 Apr;113(4):859–868. doi: 10.1016/0002-8703(87)90044-5. [DOI] [PubMed] [Google Scholar]
- Cohn L. H., DiSesa V. J., Couper G. S., Peigh P. S., Kowalker W., Collins J. J., Jr Mitral valve repair for myxomatous degeneration and prolapse of the mitral valve. J Thorac Cardiovasc Surg. 1989 Nov;98(5 Pt 2):987–993. [PubMed] [Google Scholar]
- Criley J. M., Lewis K. B., Humphries J. O., Ross R. S. Prolapse of the mitral valve: clinical and cine-angiocardiographic findings. Br Heart J. 1966 Jul;28(4):488–496. doi: 10.1136/hrt.28.4.488. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Danchin N., Voiriot P., Briancon S., Bairati I., Mathieu P., Deschamps J. P., Dureux J. B., Cherrier F. Mitral valve prolapse as a risk factor for infective endocarditis. Lancet. 1989 Apr 8;1(8641):743–745. doi: 10.1016/s0140-6736(89)92571-3. [DOI] [PubMed] [Google Scholar]
- Deloche A., Jebara V. A., Relland J. Y., Chauvaud S., Fabiani J. N., Perier P., Dreyfus G., Mihaileanu S., Carpentier A. Valve repair with Carpentier techniques. The second decade. J Thorac Cardiovasc Surg. 1990 Jun;99(6):990–1002. [PubMed] [Google Scholar]
- Devereux R. B., Hawkins I., Kramer-Fox R., Lutas E. M., Hammond I. W., Spitzer M. C., Hochreiter C., Roberts R. B., Belkin R. N., Kligfield P. Complications of mitral valve prolapse. Disproportionate occurrence in men and older patients. Am J Med. 1986 Nov;81(5):751–758. doi: 10.1016/0002-9343(86)90339-6. [DOI] [PubMed] [Google Scholar]
- Devereux R. B., Jones E. C., Roman M. J., Howard B. V., Fabsitz R. R., Liu J. E., Palmieri V., Welty T. K., Lee E. T. Prevalence and correlates of mitral valve prolapse in a population-based sample of American Indians: the Strong Heart Study. Am J Med. 2001 Dec 15;111(9):679–685. doi: 10.1016/s0002-9343(01)00981-0. [DOI] [PubMed] [Google Scholar]
- Devereux R. B. Recent developments in the diagnosis and management of mitral valve prolapse. Curr Opin Cardiol. 1995 Mar;10(2):107–116. doi: 10.1097/00001573-199503000-00003. [DOI] [PubMed] [Google Scholar]
- Disse S., Abergel E., Berrebi A., Houot A. M., Le Heuzey J. Y., Diebold B., Guize L., Carpentier A., Corvol P., Jeunemaitre X. Mapping of a first locus for autosomal dominant myxomatous mitral-valve prolapse to chromosome 16p11.2-p12.1. Am J Hum Genet. 1999 Nov;65(5):1242–1251. doi: 10.1086/302624. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Düren D. R., Becker A. E., Dunning A. J. Long-term follow-up of idiopathic mitral valve prolapse in 300 patients: a prospective study. J Am Coll Cardiol. 1988 Jan;11(1):42–47. doi: 10.1016/0735-1097(88)90164-7. [DOI] [PubMed] [Google Scholar]
- Enriquez-Sarano M., Schaff H. V., Orszulak T. A., Tajik A. J., Bailey K. R., Frye R. L. Valve repair improves the outcome of surgery for mitral regurgitation. A multivariate analysis. Circulation. 1995 Feb 15;91(4):1022–1028. doi: 10.1161/01.cir.91.4.1022. [DOI] [PubMed] [Google Scholar]
- Flack J. M., Kvasnicka J. H., Gardin J. M., Gidding S. S., Manolio T. A., Jacobs D. R., Jr Anthropometric and physiologic correlates of mitral valve prolapse in a biethnic cohort of young adults: the CARDIA study. Am Heart J. 1999 Sep;138(3 Pt 1):486–492. doi: 10.1016/s0002-8703(99)70151-1. [DOI] [PubMed] [Google Scholar]
- Fontana M. E., Pence H. L., Leighton R. F., Wooley C. F. The varying clinical spectrum of the systolic click-late systolic murmur syndrome. Circulation. 1970 May;41(5):807–816. doi: 10.1161/01.cir.41.5.807. [DOI] [PubMed] [Google Scholar]
- Fornes P., Heudes D., Fuzellier J. F., Tixier D., Bruneval P., Carpentier A. Correlation between clinical and histologic patterns of degenerative mitral valve insufficiency: a histomorphometric study of 130 excised segments. Cardiovasc Pathol. 1999 Mar-Apr;8(2):81–92. doi: 10.1016/s1054-8807(98)00021-0. [DOI] [PubMed] [Google Scholar]
- Freed L. A., Levy D., Levine R. A., Larson M. G., Evans J. C., Fuller D. L., Lehman B., Benjamin E. J. Prevalence and clinical outcome of mitral-valve prolapse. N Engl J Med. 1999 Jul 1;341(1):1–7. doi: 10.1056/NEJM199907013410101. [DOI] [PubMed] [Google Scholar]
- Gilon D., Buonanno F. S., Joffe M. M., Leavitt M., Marshall J. E., Kistler J. P., Levine R. A. Lack of evidence of an association between mitral-valve prolapse and stroke in young patients. N Engl J Med. 1999 Jul 1;341(1):8–13. doi: 10.1056/NEJM199907013410102. [DOI] [PubMed] [Google Scholar]
- Goldman M. E., Mora F., Guarino T., Fuster V., Mindich B. P. Mitral valvuloplasty is superior to valve replacement for preservation of left ventricular function: an intraoperative two-dimensional echocardiographic study. J Am Coll Cardiol. 1987 Sep;10(3):568–575. doi: 10.1016/s0735-1097(87)80199-7. [DOI] [PubMed] [Google Scholar]
- Jebara V. A., Mihaileanu S., Acar C., Brizard C., Grare P., Latremouille C., Chauvaud S., Fabiani J. N., Deloche A., Carpentier A. Left ventricular outflow tract obstruction after mitral valve repair. Results of the sliding leaflet technique. Circulation. 1993 Nov;88(5 Pt 2):II30–II34. [PubMed] [Google Scholar]
- Kligfield P., Levy D., Devereux R. B., Savage D. D. Arrhythmias and sudden death in mitral valve prolapse. Am Heart J. 1987 May;113(5):1298–1307. doi: 10.1016/0002-8703(87)90958-6. [DOI] [PubMed] [Google Scholar]
- Krahn A. D., Manfreda J., Tate R. B., Mathewson F. A., Cuddy T. E. The natural history of electrocardiographic preexcitation in men. The Manitoba Follow-up Study. Ann Intern Med. 1992 Mar 15;116(6):456–460. doi: 10.7326/0003-4819-116-6-456. [DOI] [PubMed] [Google Scholar]
- Kumar N., Kumar M., Duran C. M. A revised terminology for recording surgical findings of the mitral valve. J Heart Valve Dis. 1995 Jan;4(1):70–77. [PubMed] [Google Scholar]
- Kyndt F., Schott J. J., Trochu J. N., Baranger F., Herbert O., Scott V., Fressinaud E., David A., Moisan J. P., Bouhour J. B. Mapping of X-linked myxomatous valvular dystrophy to chromosome Xq28. Am J Hum Genet. 1998 Mar;62(3):627–632. doi: 10.1086/301747. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lambert A. S., Miller J. P., Merrick S. H., Schiller N. B., Foster E., Muhiudeen-Russell I., Cahalan M. K. Improved evaluation of the location and mechanism of mitral valve regurgitation with a systematic transesophageal echocardiography examination. Anesth Analg. 1999 Jun;88(6):1205–1212. doi: 10.1097/00000539-199906000-00004. [DOI] [PubMed] [Google Scholar]
- Levine R. A., Handschumacher M. D., Sanfilippo A. J., Hagege A. A., Harrigan P., Marshall J. E., Weyman A. E. Three-dimensional echocardiographic reconstruction of the mitral valve, with implications for the diagnosis of mitral valve prolapse. Circulation. 1989 Sep;80(3):589–598. doi: 10.1161/01.cir.80.3.589. [DOI] [PubMed] [Google Scholar]
- Levine R. A., Stathogiannis E., Newell J. B., Harrigan P., Weyman A. E. Reconsideration of echocardiographic standards for mitral valve prolapse: lack of association between leaflet displacement isolated to the apical four chamber view and independent echocardiographic evidence of abnormality. J Am Coll Cardiol. 1988 May;11(5):1010–1019. doi: 10.1016/s0735-1097(98)90059-6. [DOI] [PubMed] [Google Scholar]
- Levine R. A., Triulzi M. O., Harrigan P., Weyman A. E. The relationship of mitral annular shape to the diagnosis of mitral valve prolapse. Circulation. 1987 Apr;75(4):756–767. doi: 10.1161/01.cir.75.4.756. [DOI] [PubMed] [Google Scholar]
- Levy D., Savage D. Prevalence and clinical features of mitral valve prolapse. Am Heart J. 1987 May;113(5):1281–1290. doi: 10.1016/0002-8703(87)90956-2. [DOI] [PubMed] [Google Scholar]
- Marks A. R., Choong C. Y., Sanfilippo A. J., Ferré M., Weyman A. E. Identification of high-risk and low-risk subgroups of patients with mitral-valve prolapse. N Engl J Med. 1989 Apr 20;320(16):1031–1036. doi: 10.1056/NEJM198904203201602. [DOI] [PubMed] [Google Scholar]
- Maron B. J., Casey S. A., Poliac L. C., Gohman T. E., Almquist A. K., Aeppli D. M. Clinical course of hypertrophic cardiomyopathy in a regional United States cohort. JAMA. 1999 Feb 17;281(7):650–655. doi: 10.1001/jama.281.7.650. [DOI] [PubMed] [Google Scholar]
- McKinsey D. S., Ratts T. E., Bisno A. L. Underlying cardiac lesions in adults with infective endocarditis. The changing spectrum. Am J Med. 1987 Apr;82(4):681–688. doi: 10.1016/0002-9343(87)90001-5. [DOI] [PubMed] [Google Scholar]
- Meyers D. G., Starke H., Pearson P. H., Wilken M. K. Mitral valve prolapse in anorexia nervosa. Ann Intern Med. 1986 Sep;105(3):384–386. doi: 10.7326/0003-4819-105-3-384. [DOI] [PubMed] [Google Scholar]
- Mihaileanu S., Marino J. P., Chauvaud S., Perier P., Forman J., Vissoat J., Julien J., Dreyfus G., Abastado P., Carpentier A. Left ventricular outflow obstruction after mitral valve repair (Carpentier's technique). Proposed mechanisms of disease. Circulation. 1988 Sep;78(3 Pt 2):I78–I84. [PubMed] [Google Scholar]
- Nishimura R. A., McGoon M. D. Perspectives on mitral-valve prolapse. N Engl J Med. 1999 Jul 1;341(1):48–50. doi: 10.1056/NEJM199907013410109. [DOI] [PubMed] [Google Scholar]
- Nishimura R. A., McGoon M. D., Shub C., Miller F. A., Jr, Ilstrup D. M., Tajik A. J. Echocardiographically documented mitral-valve prolapse. Long-term follow-up of 237 patients. N Engl J Med. 1985 Nov 21;313(21):1305–1309. doi: 10.1056/NEJM198511213132101. [DOI] [PubMed] [Google Scholar]
- Ormiston J. A., Shah P. M., Tei C., Wong M. Size and motion of the mitral valve annulus in man. II. Abnormalities in mitral valve prolapse. Circulation. 1982 Apr;65(4):713–719. doi: 10.1161/01.cir.65.4.713. [DOI] [PubMed] [Google Scholar]
- REID J. V. Mid-systolic clicks. S Afr Med J. 1961 Apr 29;35:353–355. [PubMed] [Google Scholar]
- RONAN J. A., PERLOFF J. K., HARVEY W. P. SYSTOLIC CLICKS AND THE LATE SYSTOLIC MURMUR; INTRACARDIAC PHONOCARDIOGRAPHIC EVIDENCE OF THEIR MITRAL VALVE ORIGIN. Am Heart J. 1965 Sep;70:319–325. doi: 10.1016/0002-8703(65)90179-1. [DOI] [PubMed] [Google Scholar]
- Rippe J. M., Sloss L. J., Angoff G., Alpert J. S. Mitral valve prolapse in adults with congenital heart disease. Am Heart J. 1979 May;97(5):561–573. doi: 10.1016/0002-8703(79)90182-0. [DOI] [PubMed] [Google Scholar]
- Sousa Uva M., Dreyfus G., Rescigno G., al Aile N., Mascagni R., La Marra M., Pouillart F., Pargaonkar S., Palsky E., Raffoul R. Surgical treatment of asymptomatic and mildly symptomatic mitral regurgitation. J Thorac Cardiovasc Surg. 1996 Nov;112(5):1240–1249. doi: 10.1016/s0022-5223(96)70137-x. [DOI] [PubMed] [Google Scholar]
- Stewart W. J., Currie P. J., Salcedo E. E., Klein A. L., Marwick T., Agler D. A., Homa D., Cosgrove D. M. Evaluation of mitral leaflet motion by echocardiography and jet direction by Doppler color flow mapping to determine the mechanisms of mitral regurgitation. J Am Coll Cardiol. 1992 Nov 15;20(6):1353–1361. doi: 10.1016/0735-1097(92)90248-l. [DOI] [PubMed] [Google Scholar]
- Stoddard M. F., Prince C. R., Dillon S., Longaker R. A., Morris G. T., Liddell N. E. Exercise-induced mitral regurgitation is a predictor of morbid events in subjects with mitral valve prolapse. J Am Coll Cardiol. 1995 Mar 1;25(3):693–699. doi: 10.1016/0735-1097(94)00408-i. [DOI] [PubMed] [Google Scholar]
- Tribouilloy C. M., Enriquez-Sarano M., Schaff H. V., Orszulak T. A., Bailey K. R., Tajik A. J., Frye R. L. Impact of preoperative symptoms on survival after surgical correction of organic mitral regurgitation: rationale for optimizing surgical indications. Circulation. 1999 Jan 26;99(3):400–405. doi: 10.1161/01.cir.99.3.400. [DOI] [PubMed] [Google Scholar]
- Veyrat C., Ameur A., Bas S., Lessana A., Abitbol G., Kalmanson D. Pulsed Doppler echocardiographic indices for assessing mitral regurgitation. Br Heart J. 1984 Feb;51(2):130–138. doi: 10.1136/hrt.51.2.130. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Veyrat C., Pellerin D., Sainte Beuve D., Larrazet F., Kalmanson D., Witchitz S. Colour doppler valvar and subvalvar flow diameter imaging versus echo score in mitral stenosis: comparison with type of surgery. Heart. 1996 May;75(5):486–491. doi: 10.1136/hrt.75.5.486. [DOI] [PMC free article] [PubMed] [Google Scholar]








