NEUROSCIENCE. For the article “Mifepristone (RU486) protects Purkinje cells from cell death in organotypic slice cultures of postnatal rat and mouse cerebellum,” by A. M. Ghoumari, I. Dusart, M. El-Etr, F. Tronche, C. Sotelo, M. Schumacher, and E.-E. Baulieu, which appeared in issue 13, June 24, 2003, of Proc. Natl. Acad. Sci. USA (100, 7953–7958; First Published June 16, 2003; 10.1073/pnas.1332667100), the authors note that “(suppress cultures)” should be removed from the Fig. 2 legend, and that “and mouse” should be removed from the first sentence of the Fig. 5 legend. The sentence should have read, “Purkinje cell death in organotypic slice cultures of postnatal rat cerebella does not result from oxidative stress.” The figures and their corrected legends appear below.
Fig. 2.
Effects of RU486 on Purkinje cell survival in P5 and P7 rat cerebella. Organotypic slices of P5 and P7 rat cerebella (A and B, respectively) were cultured for 5 DIV in the absence (A and B) or presence (A′ and B′) of 20 μM RU486. At all ages, RU486 protects Purkinje neurons from cell death. (Scale bar = 250 μm.)
Fig. 5.
Purkinje cell death in organotypic slice cultures of postnatal rat cerebella does not result from oxidative stress. P3 cerebellar slices were treated with different antioxidant agents. (A) VitE (50 μM), NAC (5 mM), and GSH were used alone or in combination. (B) MnTBAP (200 μM), a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger, was also used.