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. 1993 Apr;37(4):901–902. doi: 10.1128/aac.37.4.901

Antimicrobial effects of a new carboxyquinolone drug, Q-35, on five serogroups of Leptospira interrogans.

I Takashima 1, M Ngoma 1, N Hashimoto 1
PMCID: PMC187807  PMID: 8388204

Abstract

New carboxyquinolone drugs, including the recently developed Q-35, were evaluated for their in vitro potency against five serogroups of Leptospira interrogans. Q-35, ofloxacin, ciprofloxacin, and tosufloxacin showed MICs (0.05 to 0.20 microgram/ml) comparable to those of tetracycline. However, MBCs of these drugs varied between 10- and 100-fold above the MIC for most strains tested. Q-35 was shown to be active against L. interrogans in vitro as judged by the MICs obtained.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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