Abstract
The density of a defined volume of the human lung can be measured in vivo by a new noninvasive technique. A beam of gamma-rays is directed at the lung and, by measuring the scattered gamma-rays, lung density is calculated. The density in the lower lobe of the right lung in normal man during quiet breathing in the sitting position ranged from 0.25 to 0.37 g.cm-3. Subnormal values were found in patients with emphsema. In patients with pulmonary congestion and edema, lung density values ranged from 0.33 to 0.93 g.cm-3. The lung density measurement correlated well with the findings in chest radiographs but the lung density values were more sensitive indices. This was particularly evident in serial observations of individual patients.
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- Chait A. Interstitial pulmonary edema. Circulation. 1972 Jun;45(6):1323–1330. doi: 10.1161/01.cir.45.6.1323. [DOI] [PubMed] [Google Scholar]
- Chinard F. P. Estimation of extravascular lung water by indicator-dilution techniques. Circ Res. 1975 Aug;37(2):137–145. doi: 10.1161/01.res.37.2.137. [DOI] [PubMed] [Google Scholar]
- Garnett E. S., Kennett T. J., Kenyon D. B., Webber C. E. A photon scattering technique for the measurement of absolute bone density in man. Radiology. 1973 Jan;106(1):209–212. doi: 10.1148/106.1.209. [DOI] [PubMed] [Google Scholar]
- Grainger R. G. Letter: Septal lines. Lancet. 1976 Apr 3;1(7962):753–753. doi: 10.1016/s0140-6736(76)93137-8. [DOI] [PubMed] [Google Scholar]
- Kennett T. J., Webber C. E. Bone density measured by photon scattering. II. Inherent sources of error. Phys Med Biol. 1976 Sep;21(5):770–780. doi: 10.1088/0031-9155/21/5/006. [DOI] [PubMed] [Google Scholar]
- Reiss K. H., Schuster W. Quantitative measurements of lung function in children by means of Compton backscatter. Radiology. 1972 Mar;102(3):613–617. doi: 10.1148/102.3.613. [DOI] [PubMed] [Google Scholar]
- Staub N. C. Pulmonary edema. Physiol Rev. 1974 Jul;54(3):678–811. doi: 10.1152/physrev.1974.54.3.678. [DOI] [PubMed] [Google Scholar]
- Webber C. E., Kennett T. J. Bone density measured by photon scattering. I. A system for clinical use. Phys Med Biol. 1976 Sep;21(5):760–769. doi: 10.1088/0031-9155/21/5/005. [DOI] [PubMed] [Google Scholar]