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. 1977 Mar 19;116(6):635–640.

DiGeorge syndrome presenting as severe congenital heart disease in the newborn.

J P Finley, G F Collins, J P de Chadarévian, R L Williams
PMCID: PMC1879194  PMID: 608163

Abstract

In seven infants with DiGeorge syndrome the major clinical manifestation was cardiac failure in the 1st week of life. All had severe congenital heart disease: five had interruption of the aortic arch and associated lesions, one had a ventricular septal defect and a cervical aorta, and one had truncus arteriosus. All but one died by 2 weeks of age. Necropsy data lent support to the hypothesis of a relation between the cardiovascular anomalies and defective development of structures derived from the third and fourth pharyngeal pouches.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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