Abstract
A 43-year old woman had recurrent massive intraperitoneal hemorrhage from rupture of a hemorrhagic corpus luteum in two successive menstrual cycles while receiving anticoagulant therapy. Left oophorectomy was performed on the first occasion and right salpingo-oophorectomy with left salpingectomy on the second. While the precise incidence cannot be determined, rupture from a hemorrhagic corpus luteum appears to be a rare but potentially catastrophic complication of anticoagulant therapy. Hence possible ovarian hemorrhage should be considered in women of reproductive age receiving heparin or sodium warfarin therapy.
Full text
PDF

Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Dacus R. M., 3rd Massive intraperitoneal hemorrhage from a corpus leteum hematoma in women taking anticoagulants. Report of 2 cases. Obstet Gynecol. 1968 Apr;31(4):471–474. [PubMed] [Google Scholar]
- FITZGERALD J. A., BERRIGAN M. V. Accurate diagnosis of ovarian vascular accidents; review of 32 instances, with clinical conclusions. Obstet Gynecol. 1959 Feb;13(2):175–180. [PubMed] [Google Scholar]
- GUREWICH V., THOMAS D. Massive intraperitoneal hemorrhage from a ruptured corpus luteum: a rare complication of long-term anticoagulant therapy. N Engl J Med. 1960 Nov 3;263:909–910. doi: 10.1056/NEJM196011032631809. [DOI] [PubMed] [Google Scholar]
- Manny J., Merin G., Rozin R. R., Freund U., Borman J. B. Ovarian hemorrhage complicating anticoagulant therapy. Obstet Gynecol. 1973 Apr;41(4):512–514. [PubMed] [Google Scholar]
- WESELEY A. C., NEUSTADTER M. I., LEVINE W. Massive intraperitoneal hemorrhage of ovarian follicular origin during anticoagulant therapy. Am J Obstet Gynecol. 1957 Mar;73(3):683–685. doi: 10.1016/s0002-9378(16)37441-5. [DOI] [PubMed] [Google Scholar]
- Walton L. A. Bleeding corpus luteum from anticoagulation therapy. Obstet Gynecol. 1969 Mar;33(3):450–450. [PubMed] [Google Scholar]
