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. 1993 May;37(5):1174–1176. doi: 10.1128/aac.37.5.1174

Susceptibilities of beta-lactamase-positive and -negative strains of Campylobacter coli to beta-lactam agents.

N Lachance 1, C Gaudreau 1, F Lamothe 1, F Turgeon 1
PMCID: PMC187926  PMID: 8390812

Abstract

The percentages of susceptibility of 28 strains of Campylobacter coli to beta-lactam agents were 96% for amoxicillin and ampicillin, 57% for ticarcillin, 4% for cefoxitin and cefuroxime, 61% for cefotaxime, and 11% for ceftazidime. None of the strains were susceptible to penicillin G, piperacillin, cefazolin, cephalothin, cefamandole, and cefoperazone. All strains were susceptible to imipenem and ciprofloxacin, and 21% were susceptible to erythromycin. A beta-lactamase was detected in 68% of the strains by cefinase disks and by the nitrocefin method. The beta-lactamase-positive strains were significantly less susceptible to amoxicillin, ampicillin, and ticarcillin than the beta-lactamase-negative strains (P < or = 0.003). Clavulanic acid (0.25 microgram/ml) but not sulbactam and tazobactam (2 micrograms/ml) lowered to susceptible levels the amoxicillin and ampicillin MICs of the only strain of C. coli resistant to amoxicillin, ampicillin, and ticarcillin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bourgault A. M., Rosenblatt J. E. Characterization of anaerobic gram-negative bacilli by using rapid slide tests for beta-lactamase production. J Clin Microbiol. 1979 Jun;9(6):654–656. doi: 10.1128/jcm.9.6.654-656.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Fliegelman R. M., Petrak R. M., Goodman L. J., Segreti J., Trenholme G. M., Kaplan R. L. Comparative in vitro activities of twelve antimicrobial agents against Campylobacter species. Antimicrob Agents Chemother. 1985 Mar;27(3):429–430. doi: 10.1128/aac.27.3.429. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Gaudreau C. L., Lariviere L. A., Lauzer J. C., Turgeon F. F. Effect of clavulanic acid on susceptibility of Campylobacter jejuni and Campylobacter coli to eight beta-lactam antibiotics. Antimicrob Agents Chemother. 1987 Jun;31(6):940–942. doi: 10.1128/aac.31.6.940. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Goossens H., De Mol P., Coignau H., Levy J., Grados O., Ghysels G., Innocent H., Butzler J. P. Comparative in vitro activities of aztreonam, ciprofloxacin, norfloxacin, ofloxacin, HR 810 (a new cephalosporin), RU28965 (a new macrolide), and other agents against enteropathogens. Antimicrob Agents Chemother. 1985 Mar;27(3):388–392. doi: 10.1128/aac.27.3.388. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Lachance N., Gaudreau C., Lamothe F., Larivière L. A. Role of the beta-lactamase of Campylobacter jejuni in resistance to beta-lactam agents. Antimicrob Agents Chemother. 1991 May;35(5):813–818. doi: 10.1128/aac.35.5.813. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Ng L. K., Stiles M. E., Taylor D. E. Inhibition of Campylobacter coli and Campylobacter jejuni by antibiotics used in selective growth media. J Clin Microbiol. 1985 Oct;22(4):510–514. doi: 10.1128/jcm.22.4.510-514.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Rautelin H., Renkonen O. V., Kosunen T. U. Emergence of fluoroquinolone resistance in Campylobacter jejuni and Campylobacter coli in subjects from Finland. Antimicrob Agents Chemother. 1991 Oct;35(10):2065–2069. doi: 10.1128/aac.35.10.2065. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Sagara H., Mochizuki A., Okamura N., Nakaya R. Antimicrobial resistance of Campylobacter jejuni and Campylobacter coli with special reference to plasmid profiles of Japanese clinical isolates. Antimicrob Agents Chemother. 1987 May;31(5):713–719. doi: 10.1128/aac.31.5.713. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Secker D. A. Erythromycin resistance only found in Campylobacter coli. J Antimicrob Chemother. 1983 Oct;12(4):414–415. doi: 10.1093/jac/12.4.414. [DOI] [PubMed] [Google Scholar]
  10. Sjögren E., Kaijser B., Werner M. Antimicrobial susceptibilities of Campylobacter jejuni and Campylobacter coli isolated in Sweden: a 10-year follow-up report. Antimicrob Agents Chemother. 1992 Dec;36(12):2847–2849. doi: 10.1128/aac.36.12.2847. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Taylor D. N., Blaser M. J., Echeverria P., Pitarangsi C., Bodhidatta L., Wang W. L. Erythromycin-resistant Campylobacter infections in Thailand. Antimicrob Agents Chemother. 1987 Mar;31(3):438–442. doi: 10.1128/aac.31.3.438. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Wang W. L., Reller L. B., Blaser M. J. Comparison of antimicrobial susceptibility patterns of Campylobacter jejuni and Campylobacter coli. Antimicrob Agents Chemother. 1984 Sep;26(3):351–353. doi: 10.1128/aac.26.3.351. [DOI] [PMC free article] [PubMed] [Google Scholar]

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