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. 1989 Sep;135(3):565–570.

Macrophage multinucleation is accompanied by the expression of new soluble and membrane antigens in mice.

A Vignery 1
PMCID: PMC1879880  PMID: 2675626

Abstract

Polyclonal antibodies were raised against mouse multinucleated giant cells to identify proteins specifically associated with multinucleated macrophages. A 115 kd membrane protein and a 160 kd soluble protein were detected by immunoprecipitation of radiolabeled giant cells and were not seen in mononucleated macrophages. This study demonstrated that giant cells express de novo synthesized proteins that are not present in macrophages and identified a new immunization technique to generate antibodies directed against cell surface components.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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