Abstract
It is important to differentiate worsening of a cutaneous eruption following topical therapy from lack of response to the medication. A study to determine the origin of contact dermatitis secondary to topical therapy was conducted among 87 patients with this kind of contact dermatitis. Sixteen patch tests with chemical compounds known to be allergenic were done. The following eight chemical compounds were responsible for 86.5% of the positive reactions observed: neomycin, ethylenediamine, mercury, benzocaine, iodochlorhydroxyquin, peruvian balsam, nitrofurazone and cinchocaine. More than half of the reactions were to neomycin, ethylenediamine and mercury. It is easier to diagnose this condition if one knows the composition of the topical medications one prescribes and the allergenic potency of their ingredients.
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Selected References
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- Bandmann H. J., Calnan C. D., Cronin E., Fregert S., Hjorth N., Magnusson B., Maibach H., Malten K. E., Meneghini C. L., Pirilä V. Dermatitis from applied medicaments. Arch Dermatol. 1972 Sep;106(3):335–337. [PubMed] [Google Scholar]
- Burry J. N., Kirk J., Reid J. G., Turner T. Environmental dermatitis: patch tests in 1,000 cases of allergic contact dermatitis. Med J Aust. 1973 Oct 6;2(14):681–685. doi: 10.5694/j.1326-5377.1973.tb129702.x. [DOI] [PubMed] [Google Scholar]
- Durocher L. P., Lassonde M. Les dermites par contact. Union Med Can. 1973 Dec;102(12):2528–2532. [PubMed] [Google Scholar]
- Schorr W. F., Wenzel F. J., Hededus S. I. Cross-sensitivity and aminoglycoside antibiotics. Arch Dermatol. 1973 Apr;107(4):533–539. [PubMed] [Google Scholar]