Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1993 Sep;37(9):1986–1988. doi: 10.1128/aac.37.9.1986

Comparison of the in vitro activities of various parenteral and oral antimicrobial agents against endemic Haemophilus ducreyi.

K E Aldridge 1, C Cammarata 1, D H Martin 1
PMCID: PMC188105  PMID: 8239617

Abstract

The in vitro susceptibilities to various antimicrobial agents of 100 strains of beta-lactamase-producing Haemophilus ducreyi recently isolated from patients in New Orleans, La., were determined by an agar dilution method. All strains were highly susceptible to ceftizoxime, ceftriaxone, ceftazidime, azithromycin, erythromycin, ciprofloxacin, and sparfloxacin. beta-Lactam-beta-lactamase inhibitor combinations were less active, but all strains were susceptible to them. Doxycycline exhibited the poorest activity, and the rate of resistance to doxycycline varied depending on the time after inoculation that the MIC was determined.

Full text

PDF
1986

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Albritton W. L., Brunton J. L., Slaney L., MacLean I. Plasmid-mediated sulfonamide resistance in Haemophilus ducreyi. Antimicrob Agents Chemother. 1982 Jan;21(1):159–165. doi: 10.1128/aac.21.1.159. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bilgeri Y. R., Ballard R. C., Duncan M. O., Mauff A. C., Koornhof H. J. Antimicrobial susceptibility of 103 strains of Haemophilus ducreyi isolated in Johannesburg. Antimicrob Agents Chemother. 1982 Oct;22(4):686–688. doi: 10.1128/aac.22.4.686. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bowmer M. I., Nsanze H., D'Costa L. J., Dylewski J., Fransen L., Piot P., Ronald A. R. Single-dose ceftriaxone for chancroid. Antimicrob Agents Chemother. 1987 Jan;31(1):67–69. doi: 10.1128/aac.31.1.67. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dangor Y., Ballard R. C., Miller S. D., Koornhof H. J. Antimicrobial susceptibility of Haemophilus ducreyi. Antimicrob Agents Chemother. 1990 Jul;34(7):1303–1307. doi: 10.1128/aac.34.7.1303. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Girouard Y. C., Maclean I. W., Ronald A. R., Albritton W. L. Synergistic antibacterial activity of clavulanic acid and amoxicillin against beta-lactamase-producing strains of Haemophilus ducreyi. Antimicrob Agents Chemother. 1981 Jul;20(1):144–145. doi: 10.1128/aac.20.1.144. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Hammond G. W., Slutchuk M., Lian C. J., Wilt J. C., Ronald A. R. The treatment of chancroid: comparison of one week of sulfisoxazole with single dose doxycycline. J Antimicrob Chemother. 1979 May;5(3):261–265. doi: 10.1093/jac/5.3.261. [DOI] [PubMed] [Google Scholar]
  7. Sanson-Le Pors M. J., Casin I., Ortenberg M., Perol Y. In-vitro susceptibility of thirty strains of Haemophilus ducreyi to several antibiotics including six cephalosporins. J Antimicrob Chemother. 1983 Mar;11(3):271–280. doi: 10.1093/jac/11.3.271. [DOI] [PubMed] [Google Scholar]
  8. Schmid G. P. The treatment of chancroid. JAMA. 1986 Apr 4;255(13):1757–1762. [PubMed] [Google Scholar]
  9. Schmid G. P. Treatment of chancroid, 1989. Rev Infect Dis. 1990 Jul-Aug;12 (Suppl 6):S580–S589. doi: 10.1093/clinids/12.supplement_6.s580. [DOI] [PubMed] [Google Scholar]
  10. Slaney L., Chubb H., Ronald A., Brunham R. In-vitro activity of azithromycin, erythromycin, ciprofloxacin and norfloxacin against Neisseria gonorrhoeae, Haemophilus ducreyi, and Chlamydia trachomatis. J Antimicrob Chemother. 1990 Jan;25 (Suppl A):1–5. doi: 10.1093/jac/25.suppl_a.1. [DOI] [PubMed] [Google Scholar]
  11. Wasserheit J. N. Epidemiological synergy. Interrelationships between human immunodeficiency virus infection and other sexually transmitted diseases. Sex Transm Dis. 1992 Mar-Apr;19(2):61–77. [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES