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. 1994 Jun;38(6):1419–1421. doi: 10.1128/aac.38.6.1419

Neuronal monoamine reuptake inhibitors enhance in vitro susceptibility to chloroquine in resistant Plasmodium falciparum.

A F Coutaux 1, J J Mooney 1, D F Wirth 1
PMCID: PMC188223  PMID: 8092848

Abstract

Chloroquine resistance in Plasmodium falciparum was reversed in vitro by the neuronal monoamine reuptake inhibitors and antidepressants desipramine, sertraline, fluoxetine, and norfluoxetine but not by carbamazepine, an antiseizure and mood-stabilizing tricyclic drug resembling desipramine which only weakly inhibits neuronal monoamine reuptake. These findings have important clinical implications for drug combination therapy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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