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. 1994 Nov;38(11):2668–2670. doi: 10.1128/aac.38.11.2668

Antimicrobial resistance of Shigella isolates causing traveler's diarrhea.

J Vila 1, J Gascon 1, S Abdalla 1, J Gomez 1, F Marco 1, A Moreno 1, M Corachan 1, T Jimenez de Anta 1
PMCID: PMC188262  PMID: 7872767

Abstract

Shigella isolates were identified as a cause of traveler's diarrhea in 67 (10%) of 675 patients and were tested for resistance to seven antimicrobial agents in a comparative study with those causing nontraveler's diarrhea in Spain. Ampicillin and chloramphenicol resistance was more frequent in Shigella flexneri (60 and 46%, respectively) than in Shigella sonnei (32 and 18%, respectively) and in travel-related isolates (P < 0.05 and 0.04, respectively). Of S. sonnei isolates from patients with traveler's diarrhea, 73 and 54% showed tetracycline and trimethoprim-sulfamethoxazole resistance, respectively, compared with only 8% of isolates from patients without a history of travel to developing countries (P < 0.007 and P < 0.0002). Low-level resistance to cephalosporins was found, whereas quinolone-resistant strains were not detected among travel-related Shigella isolates. Thus, quinolones may be an effective alternative therapy for travel-related shigellosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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