Abstract
OBJECTIVES--To determine the incidence of oral cancer in Scotland between 1960 and 1989 and oral cancer mortality from 1911 to 1989. SETTING--Data were obtained on oral cancer incidence from the information and statistics division of the Common Services Agency of the Scottish Health Service and mortality data from the office of the registrar general for Scotland. RESULTS--Mortality from intraoral cancers in Scotland substantially declined throughout this century until the mid-1970s. This trend, however, was then reversed, and fourfold increases in incidence were observed in younger age groups after 1960. Death rates in these younger age groups increased to levels previously recorded in the 1940s. These increases seemed to be cohort based and may therefore continue into the future. CONCLUSIONS--Reasons for increasing rates among younger age groups are speculative and rely on combining knowledge about risk factors and available ecological data. Though increases in incidence at younger ages do not result in a large change in the number of cases diagnosed, possible similar increases continuing into older ages, when oral cancer is more common, will correspond to a much larger increase in the actual number of cases. Given that such a large attributable risk is associated with tobacco and alcohol, however, these increases may be preventable.
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- Blot W. J., McLaughlin J. K., Winn D. M., Austin D. F., Greenberg R. S., Preston-Martin S., Bernstein L., Schoenberg J. B., Stemhagen A., Fraumeni J. F., Jr Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res. 1988 Jun 1;48(11):3282–3287. [PubMed] [Google Scholar]
- Depue R. H. Rising mortality from cancer of the tongue in young white males. N Engl J Med. 1986 Sep 4;315(10):647–647. doi: 10.1056/NEJM198609043151013. [DOI] [PubMed] [Google Scholar]
- Doll R., Cook P. Summarizing indices for comparison of cancer incidence data. Int J Cancer. 1967 May 15;2(3):269–279. doi: 10.1002/ijc.2910020310. [DOI] [PubMed] [Google Scholar]
- Hakulinen T., Andersen A., Malker B., Pukkala E., Schou G., Tulinius H. Trends in cancer incidence in the Nordic countries. A collaborative study of the five Nordic Cancer Registries. Acta Pathol Microbiol Immunol Scand Suppl. 1986;288:1–151. [PubMed] [Google Scholar]
- Keller A. Z., Terris M. The association of alcohol and tobacco with cancer of the mouth and pharynx. Am J Public Health Nations Health. 1965 Oct;55(10):1578–1585. doi: 10.2105/ajph.55.10.1578. [DOI] [PMC free article] [PubMed] [Google Scholar]
- La Vecchia C., Lucchini F., Negri E., Boyle P., Maisonneuve P., Levi F. Trends of cancer mortality in Europe, 1955-1989: I, Digestive sites. Eur J Cancer. 1992;28(1):132–235. doi: 10.1016/0959-8049(92)90402-n. [DOI] [PubMed] [Google Scholar]
- Merletti F., Boffetta P., Ciccone G., Mashberg A., Terracini B. Role of tobacco and alcoholic beverages in the etiology of cancer of the oral cavity/oropharynx in Torino, Italy. Cancer Res. 1989 Sep 1;49(17):4919–4924. [PubMed] [Google Scholar]
- Møller H. Changing incidence of cancer of the tongue, oral cavity, and pharynx in Denmark. J Oral Pathol Med. 1989 Apr;18(4):224–229. doi: 10.1111/j.1600-0714.1989.tb00767.x. [DOI] [PubMed] [Google Scholar]
- RUSSELL M. H. Diverging sex-morbidity trends in cancer of the mouth; a hospital morbidity study. Br Med J. 1955 Oct 1;2(4943):823–827. doi: 10.1136/bmj.2.4943.823. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schifflers E., Smans M., Muir C. S. Birth cohort analysis using irregular cross-sectional data: a technical note. Stat Med. 1985 Jan-Mar;4(1):63–75. doi: 10.1002/sim.4780040110. [DOI] [PubMed] [Google Scholar]
- Spring J. A., Buss D. H. Three centuries of alcohol in the British diet. Nature. 1977 Dec 15;270(5638):567–572. doi: 10.1038/270567a0. [DOI] [PubMed] [Google Scholar]
- Svejda J., Kosut V. Epidemiology of malignant tumours with special regards to the orofacial region. Neoplasma. 1971;18(2):193–196. [PubMed] [Google Scholar]
- Winn D. M., Blot W. J., Shy C. M., Pickle L. W., Toledo A., Fraumeni J. F., Jr Snuff dipping and oral cancer among women in the southern United States. N Engl J Med. 1981 Mar 26;304(13):745–749. doi: 10.1056/NEJM198103263041301. [DOI] [PubMed] [Google Scholar]