Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1992 Feb;36(2):467–469. doi: 10.1128/aac.36.2.467

Identification of a ROB-1 beta-lactamase in Haemophilus ducreyi.

I W Maclean 1, L Slaney 1, J M Juteau 1, R C Levesque 1, W L Albritton 1, A R Ronald 1
PMCID: PMC188459  PMID: 1605612

Abstract

A collection of 100 clinical isolates of Haemophilus ducreyi from Thailand were all found to harbor a 5.4-kb plasmid, designated pTH126, which was shown to contain the bla ROB-1 gene. Restriction enzyme analysis and DNA-DNA hybridization studies confirmed that pTH126 was similar to the ROB-1 beta-lactamase plasmid pVM105 from Actinobacillus pleuropneumoniae. In approximately one-half of the isolates, pTH126 was found together with pHD131, which mediates TEM-1 beta-lactamase production.

Full text

PDF
467

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Albritton W. L., Bendler J. W., Setlow J. K. Plasmid transformation in Haemophilus influenzae. J Bacteriol. 1981 Feb;145(2):1099–1101. doi: 10.1128/jb.145.2.1099-1101.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Brunton J., Meier M., Erhman N., Clare D., Almawy R. Origin of small beta-lactamase-specifying plasmids in Haemophilus species and Neisseria gonorrhoeae. J Bacteriol. 1986 Oct;168(1):374–379. doi: 10.1128/jb.168.1.374-379.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Cameron D. W., Simonsen J. N., D'Costa L. J., Ronald A. R., Maitha G. M., Gakinya M. N., Cheang M., Ndinya-Achola J. O., Piot P., Brunham R. C. Female to male transmission of human immunodeficiency virus type 1: risk factors for seroconversion in men. Lancet. 1989 Aug 19;2(8660):403–407. doi: 10.1016/s0140-6736(89)90589-8. [DOI] [PubMed] [Google Scholar]
  4. Hammond G. W., Slutchuk M., Scatliff J., Sherman E., Wilt J. C., Ronald A. R. Epidemiologic, clinical, laboratory, and therapeutic features of an urban outbreak of chancroid in North America. Rev Infect Dis. 1980 Nov-Dec;2(6):867–879. doi: 10.1093/clinids/2.6.867. [DOI] [PubMed] [Google Scholar]
  5. Hirsh D. C., Martin L. D., Libal M. C. Plasmid-mediated antimicrobial resistance in Haemophilus pleuropneumoniae. Am J Vet Res. 1982 Feb;43(2):269–272. [PubMed] [Google Scholar]
  6. Juteau J. M., Levesque R. C. Sequence analysis and evolutionary perspectives of ROB-1 beta-lactamase. Antimicrob Agents Chemother. 1990 Jul;34(7):1354–1359. doi: 10.1128/aac.34.7.1354. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Livrelli V. O., Darfeuille-Richaud A., Rich C. D., Joly B. H., Martel J. L. Genetic determinant of the ROB-1 beta-lactamase in bovine and porcine Pasteurella strains. Antimicrob Agents Chemother. 1988 Aug;32(8):1282–1284. doi: 10.1128/aac.32.8.1282. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Livrelli V., Peduzzi J., Joly B. Sequence and molecular characterization of the ROB-1 beta-lactamase gene from Pasteurella haemolytica. Antimicrob Agents Chemother. 1991 Feb;35(2):242–251. doi: 10.1128/aac.35.2.242. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. McNicol P. J., Ronald A. R. The plasmids of Haemophilus ducreyi. J Antimicrob Chemother. 1984 Dec;14(6):561–564. [PubMed] [Google Scholar]
  10. Medeiros A. A., Levesque R., Jacoby G. A. An animal source for the ROB-1 beta-lactamase of Haemophilus influenzae type b. Antimicrob Agents Chemother. 1986 Feb;29(2):212–215. doi: 10.1128/aac.29.2.212. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Morse S. A. Chancroid and Haemophilus ducreyi. Clin Microbiol Rev. 1989 Apr;2(2):137–157. doi: 10.1128/cmr.2.2.137. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Schmid G. P., Sanders L. L., Jr, Blount J. H., Alexander E. R. Chancroid in the United States. Reestablishment of an old disease. JAMA. 1987 Dec 11;258(22):3265–3268. [PubMed] [Google Scholar]
  13. Sturm A. W., Stolting G. J., Cormane R. H., Zanen H. C. Clinical and microbiological evaluation of 46 episodes of genital ulceration. Genitourin Med. 1987 Apr;63(2):98–101. doi: 10.1136/sti.63.2.98. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Willson P. J., Albritton W. L., Slaney L., Setlow J. K. Characterization of a multiple antibiotic resistance plasmid from Haemophilus ducreyi. Antimicrob Agents Chemother. 1989 Sep;33(9):1627–1630. doi: 10.1128/aac.33.9.1627. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES