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. 1992 Feb;36(2):470–472. doi: 10.1128/aac.36.2.470

Use of fluoroquinolones for prophylaxis of murine Pneumocystis carinii pneumonia.

M Brun-Pascaud 1, M Fay 1, M Zhong 1, J Bauchet 1, A Dux-Guyot 1, J J Pocidalo 1
PMCID: PMC188460  PMID: 1605613

Abstract

We compared the prophylactic activities of six fluoroquinolones against Pneumocystis carinii pneumonia in immunosuppressed rats. Pefloxacin was the only agent which was as effective as the reference drug trimethoprim-sulfamethoxazole. Clinical trials with pefloxacin in patients at risk for P. carinii pneumonia appear to be justified.

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Selected References

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