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. 1995 Feb;69(2):1253–1255. doi: 10.1128/jvi.69.2.1253-1255.1995

Protection against homologous but not heterologous challenge induced by inactivated feline immunodeficiency virus vaccines.

M J Hosie 1, R Osborne 1, J K Yamamoto 1, J C Neil 1, O Jarrett 1
PMCID: PMC188698  PMID: 7815500

Abstract

Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8) which is distinct from the Petaluma strain in virus neutralization. Protection was associated with a type-specific neutralizing antibody response and was retained when the challenge virus was propagated in an unrelated cell line.

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Selected References

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