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. 1994 Aug;145(2):253–262.

Cathepsin B and other proteases in human colorectal carcinoma.

J M Jessup 1
PMCID: PMC1887384  PMID: 8053486

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Andres J. L., Rönnstrand L., Cheifetz S., Massagué J. Purification of the transforming growth factor-beta (TGF-beta) binding proteoglycan betaglycan. J Biol Chem. 1991 Dec 5;266(34):23282–23287. [PubMed] [Google Scholar]
  2. Aznavoorian S., Liotta L. A., Kupchik H. Z. Characteristics of invasive and noninvasive human colorectal adenocarcinoma cells. J Natl Cancer Inst. 1990 Sep 19;82(18):1485–1492. doi: 10.1093/jnci/82.18.1485. [DOI] [PubMed] [Google Scholar]
  3. Barsky S. H., Gopalakrishna R. Increased invasion and spontaneous metastasis of BL6 melanoma with inhibition of the desmoplastic response in C57 BL/6 mice. Cancer Res. 1987 Mar 15;47(6):1663–1667. [PubMed] [Google Scholar]
  4. Bos J. L. ras oncogenes in human cancer: a review. Cancer Res. 1989 Sep 1;49(17):4682–4689. [PubMed] [Google Scholar]
  5. Bosman F. T., de Bruïne A., Flohil C., van der Wurff A., ten Kate J., Dinjens W. W. Epithelial-stromal interactions in colon cancer. Int J Dev Biol. 1993 Mar;37(1):203–211. [PubMed] [Google Scholar]
  6. Boyd D., Florent G., Chakrabarty S., Brattain D., Brattain M. G. Alterations of the biological characteristics of a colon carcinoma cell line by colon-derived substrata material. Cancer Res. 1988 May 15;48(10):2825–2831. [PubMed] [Google Scholar]
  7. Boyd D., Florent G., Childress-Fields K., Brattain M. G. Alteration in the behavior of a colon carcinoma cell line by extracellular matrix components. Cancer Lett. 1988 Jul;41(1):81–90. doi: 10.1016/0304-3835(88)90058-4. [DOI] [PubMed] [Google Scholar]
  8. Boyd D., Florent G., Kim P., Brattain M. Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines. Cancer Res. 1988 Jun 1;48(11):3112–3116. [PubMed] [Google Scholar]
  9. Boyd D., Ziober B., Chakrabarty S., Brattain M. Examination of urokinase protein/transcript levels and their relationship with laminin degradation in cultured colon carcinoma. Cancer Res. 1989 Feb 15;49(4):816–820. [PubMed] [Google Scholar]
  10. Braulke T., Mach L., Hoflack B., Glössl J. Biosynthesis and endocytosis of lysosomal enzymes in human colon carcinoma SW 1116 cells: impaired internalization of plasma membrane-associated cation-independent mannose 6-phosphate receptor. Arch Biochem Biophys. 1992 Oct;298(1):176–181. doi: 10.1016/0003-9861(92)90109-a. [DOI] [PubMed] [Google Scholar]
  11. Buck M. R., Karustis D. G., Day N. A., Honn K. V., Sloane B. F. Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues. Biochem J. 1992 Feb 15;282(Pt 1):273–278. doi: 10.1042/bj2820273. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Buø L., Lyberg T., Jørgensen L., Johansen H. T., Aasen A. O. Location of plasminogen activator (PA) and PA inhibitor in human colorectal adenocarcinomas. APMIS. 1993 Mar;101(3):235–241. doi: 10.1111/j.1699-0463.1993.tb00106.x. [DOI] [PubMed] [Google Scholar]
  13. Campo E., Muñoz J., Miquel R., Palacín A., Cardesa A., Sloane B. F., Emmert-Buck M. R. Cathepsin B expression in colorectal carcinomas correlates with tumor progression and shortened patient survival. Am J Pathol. 1994 Aug;145(2):301–309. [PMC free article] [PubMed] [Google Scholar]
  14. Chakrabarty S., Fan D., Varani J. Modulation of differentiation and proliferation in human colon carcinoma cells by transforming growth factor beta 1 and beta 2. Int J Cancer. 1990 Sep 15;46(3):493–499. doi: 10.1002/ijc.2910460328. [DOI] [PubMed] [Google Scholar]
  15. Chakrabarty S., Mustain S., Willson J. K. Induction of carcinoembryonic antigen and its crossreactive gene products in human colonic adenomas and carcinomas by transforming growth factor-beta. Mol Biother. 1990 Mar;2(1):27–31. [PubMed] [Google Scholar]
  16. Chambers A. F., Tuck A. B. Ras-responsive genes and tumor metastasis. Crit Rev Oncog. 1993;4(2):95–114. [PubMed] [Google Scholar]
  17. Cooper A. R., Kurkinen M., Taylor A., Hogan B. L. Studies on the biosynthesis of laminin by murine parietal endoderm cells. Eur J Biochem. 1981 Sep;119(1):189–197. doi: 10.1111/j.1432-1033.1981.tb05593.x. [DOI] [PubMed] [Google Scholar]
  18. Corticchiato O., Cajot J. F., Abrahamson M., Chan S. J., Keppler D., Sordat B. Cystatin C and cathepsin B in human colon carcinoma: expression by cell lines and matrix degradation. Int J Cancer. 1992 Oct 21;52(4):645–652. doi: 10.1002/ijc.2910520425. [DOI] [PubMed] [Google Scholar]
  19. Cubellis M. V., Nolli M. L., Cassani G., Blasi F. Binding of single-chain prourokinase to the urokinase receptor of human U937 cells. J Biol Chem. 1986 Dec 5;261(34):15819–15822. [PubMed] [Google Scholar]
  20. Daneker G. W., Jr, Mercurio A. M., Guerra L., Wolf B., Salem R. R., Bagli D. J., Steele G. D., Jr Laminin expression in colorectal carcinomas varying in degree of differentiation. Arch Surg. 1987 Dec;122(12):1470–1474. doi: 10.1001/archsurg.1987.01400240118022. [DOI] [PubMed] [Google Scholar]
  21. Daneker G. W., Jr, Piazza A. J., Steele G. D., Jr, Mercurio A. M. Relationship between extracellular matrix interactions and degree of differentiation in human colon carcinoma cell lines. Cancer Res. 1989 Feb 1;49(3):681–686. [PubMed] [Google Scholar]
  22. Durdey P., Cooper J. C., Switala S., King R. F., Williams N. S. The role of peptidases in cancer of the rectum and sigmoid colon. Br J Surg. 1985 May;72(5):378–381. doi: 10.1002/bjs.1800720515. [DOI] [PubMed] [Google Scholar]
  23. Ellis V., Scully M. F., Kakkar V. V. Plasminogen activation initiated by single-chain urokinase-type plasminogen activator. Potentiation by U937 monocytes. J Biol Chem. 1989 Feb 5;264(4):2185–2188. [PubMed] [Google Scholar]
  24. Fidler I. J. Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture. Cancer Res. 1990 Oct 1;50(19):6130–6138. [PubMed] [Google Scholar]
  25. Fidler I. J., Hart I. R. Biological diversity in metastatic neoplasms: origins and implications. Science. 1982 Sep 10;217(4564):998–1003. doi: 10.1126/science.7112116. [DOI] [PubMed] [Google Scholar]
  26. Fidler I. J., Kripke M. L. Metastasis results from preexisting variant cells within a malignant tumor. Science. 1977 Aug 26;197(4306):893–895. doi: 10.1126/science.887927. [DOI] [PubMed] [Google Scholar]
  27. Fidler I. J. Tumor heterogeneity and the biology of cancer invasion and metastasis. Cancer Res. 1978 Sep;38(9):2651–2660. [PubMed] [Google Scholar]
  28. Fishel R., Lescoe M. K., Rao M. R., Copeland N. G., Jenkins N. A., Garber J., Kane M., Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell. 1993 Dec 3;75(5):1027–1038. doi: 10.1016/0092-8674(93)90546-3. [DOI] [PubMed] [Google Scholar]
  29. Forster S. J., Talbot I. C., Clayton D. G., Critchley D. R. Tumour basement membrane laminin in adenocarcinoma of rectum: an immunohistochemical study of biological and clinical significance. Int J Cancer. 1986 Jun 15;37(6):813–817. doi: 10.1002/ijc.2910370603. [DOI] [PubMed] [Google Scholar]
  30. Forster S. J., Talbot I. C., Critchley D. R. Laminin and fibronectin in rectal adenocarcinoma: relationship to tumour grade, stage and metastasis. Br J Cancer. 1984 Jul;50(1):51–61. doi: 10.1038/bjc.1984.139. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Friedman E. A., Buset M., Winawer S. J. Tumor-promoter-enhanced destruction of noninvasive human benign colon tumor cells by cocultivated carcinoma cells. Digestion. 1988;40(4):197–211. doi: 10.1159/000199656. [DOI] [PubMed] [Google Scholar]
  32. Gelister J. S., Mahmoud M., Lewin M. R., Gaffney P. J., Boulos P. B. Plasminogen activators in human colorectal neoplasia. Br Med J (Clin Res Ed) 1986 Sep 20;293(6549):728–731. doi: 10.1136/bmj.293.6549.728. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Grigioni W. F., Biagini G., Errico A. D., Milani M., Villanacci V., Garbisa S., Mattioli S., Gozzetti G., Mancini A. M. Behaviour of basement membrane antigens in gastric and colorectal cancer. Immunohistochemical study. Acta Pathol Jpn. 1986 Feb;36(2):173–184. doi: 10.1111/j.1440-1827.1986.tb01471.x. [DOI] [PubMed] [Google Scholar]
  34. Havenith M. G., Arends J. W., Simon R., Volovics A., Wiggers T., Bosman F. T. Type IV collagen immunoreactivity in colorectal cancer. Prognostic value of basement membrane deposition. Cancer. 1988 Nov 15;62(10):2207–2211. doi: 10.1002/1097-0142(19881115)62:10<2207::aid-cncr2820621023>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
  35. Hewitt R. E., Keeble W., Powe D. G., Williamson R. J., Turner D. R. The influence of local tissue environment on epithelial basement membrane continuity in colorectal carcinomas. Int J Cancer. 1994 Mar 1;56(5):675–680. doi: 10.1002/ijc.2910560512. [DOI] [PubMed] [Google Scholar]
  36. Höyhtyä M., Fridman R., Komarek D., Porter-Jordan K., Stetler-Stevenson W. G., Liotta L. A., Liang C. M. Immunohistochemical localization of matrix metalloproteinase 2 and its specific inhibitor TIMP-2 in neoplastic tissues with monoclonal antibodies. Int J Cancer. 1994 Feb 15;56(4):500–505. doi: 10.1002/ijc.2910560408. [DOI] [PubMed] [Google Scholar]
  37. Inada K., Shimokawa K., Ikeda T., Hayashi M., Azuma S. Development of liver metastasis in colorectal carcinoma. With special reference to venous invasion and basement membrane laminin. Acta Pathol Jpn. 1991 Mar;41(3):240–245. [PubMed] [Google Scholar]
  38. Ingber D. E., Madri J. A., Jamieson J. D. Role of basal lamina in neoplastic disorganization of tissue architecture. Proc Natl Acad Sci U S A. 1981 Jun;78(6):3901–3905. doi: 10.1073/pnas.78.6.3901. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Iozzo R. V., Bolender R. P., Wight T. N. Proteoglycan changes in the intercellular matrix of human colon carcinoma: an integrated biochemical and stereologic analysis. Lab Invest. 1982 Aug;47(2):124–138. [PubMed] [Google Scholar]
  40. Iozzo R. V. Neoplastic modulation of extracellular matrix. Colon carcinoma cells release polypeptides that alter proteoglycan metabolism in colon fibroblasts. J Biol Chem. 1985 Jun 25;260(12):7464–7473. [PubMed] [Google Scholar]
  41. Irimura T., Yamori T., Bennett S. C., Ota D. M., Cleary K. R. The relationship of collagenolytic activity to stage of human colorectal carcinoma. Int J Cancer. 1987 Jul 15;40(1):24–31. doi: 10.1002/ijc.2910400106. [DOI] [PubMed] [Google Scholar]
  42. Kellokumpu I., Ekblom P., Scheinin T. M., Andersson L. C. Malignant transformation in human colorectal mucosa as monitored by distribution of laminin, a basement membrane glycoprotein. Acta Pathol Microbiol Immunol Scand A. 1985 Sep;93(5):285–291. doi: 10.1111/j.1699-0463.1985.tb03952.x. [DOI] [PubMed] [Google Scholar]
  43. Keppler D., Fondanèche M. C., Dalet-Fumeron V., Pagano M., Burtin P. Immunohistochemical and biochemical study of a cathepsin B-like proteinase in human colonic cancers. Cancer Res. 1988 Dec 1;48(23):6855–6862. [PubMed] [Google Scholar]
  44. Kerbel R. S. Growth dominance of the metastatic cancer cell: cellular and molecular aspects. Adv Cancer Res. 1990;55:87–132. doi: 10.1016/s0065-230x(08)60469-8. [DOI] [PubMed] [Google Scholar]
  45. Knudson W., Bartnik E., Knudson C. B. Assembly of pericellular matrices by COS-7 cells transfected with CD44 lymphocyte-homing receptor genes. Proc Natl Acad Sci U S A. 1993 May 1;90(9):4003–4007. doi: 10.1073/pnas.90.9.4003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Kominami E., Tsukahara T., Hara K., Katunuma N. Biosyntheses and processing of lysosomal cysteine proteinases in rat macrophages. FEBS Lett. 1988 Apr 11;231(1):225–228. doi: 10.1016/0014-5793(88)80736-1. [DOI] [PubMed] [Google Scholar]
  47. Koretz K., Möller P., Schwartz-Albiez R. Plasminogen activators and plasminogen activator inhibitors in human colorectal carcinoma tissues are not expressed by the tumour cells. Eur J Cancer. 1993;29A(8):1184–1189. doi: 10.1016/s0959-8049(05)80312-0. [DOI] [PubMed] [Google Scholar]
  48. Laurie G. W., Leblond C. P. What is known of the production of basement membrane components. J Histochem Cytochem. 1983 Jan;31(1A):159–163. [PubMed] [Google Scholar]
  49. Leach F. S., Nicolaides N. C., Papadopoulos N., Liu B., Jen J., Parsons R., Peltomäki P., Sistonen P., Aaltonen L. A., Nyström-Lahti M. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell. 1993 Dec 17;75(6):1215–1225. doi: 10.1016/0092-8674(93)90330-s. [DOI] [PubMed] [Google Scholar]
  50. Lee E. C., Woo H. J., Korzelius C. A., Steele G. D., Jr, Mercurio A. M. Carbohydrate-binding protein 35 is the major cell-surface laminin-binding protein in colon carcinoma. Arch Surg. 1991 Dec;126(12):1498–1502. doi: 10.1001/archsurg.1991.01410360072011. [DOI] [PubMed] [Google Scholar]
  51. Levy A. T., Cioce V., Sobel M. E., Garbisa S., Grigioni W. F., Liotta L. A., Stetler-Stevenson W. G. Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma. Cancer Res. 1991 Jan 1;51(1):439–444. [PubMed] [Google Scholar]
  52. Liotta L. A., Rao C. N., Barsky S. H. Tumor invasion and the extracellular matrix. Lab Invest. 1983 Dec;49(6):636–649. [PubMed] [Google Scholar]
  53. Liotta L. A. Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture. Cancer Res. 1986 Jan;46(1):1–7. [PubMed] [Google Scholar]
  54. Maciewicz R. A., Wardale R. J., Etherington D. J., Paraskeva C. Immunodetection of cathepsins B and L present in and secreted from human pre-malignant and malignant colorectal tumour cell lines. Int J Cancer. 1989 Mar 15;43(3):478–486. doi: 10.1002/ijc.2910430323. [DOI] [PubMed] [Google Scholar]
  55. McDonnell S., Navre M., Coffey R. J., Jr, Matrisian L. M. Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas. Mol Carcinog. 1991;4(6):527–533. doi: 10.1002/mc.2940040617. [DOI] [PubMed] [Google Scholar]
  56. Miyazaki K., Hattori Y., Umenishi F., Yasumitsu H., Umeda M. Purification and characterization of extracellular matrix-degrading metalloproteinase, matrin (pump-1), secreted from human rectal carcinoma cell line. Cancer Res. 1990 Dec 15;50(24):7758–7764. [PubMed] [Google Scholar]
  57. Moin K., Day N. A., Sameni M., Hasnain S., Hirama T., Sloane B. F. Human tumour cathepsin B. Comparison with normal liver cathepsin B. Biochem J. 1992 Jul 15;285(Pt 2):427–434. doi: 10.1042/bj2850427. [DOI] [PMC free article] [PubMed] [Google Scholar]
  58. Morgan D. O., Edman J. C., Standring D. N., Fried V. A., Smith M. C., Roth R. A., Rutter W. J. Insulin-like growth factor II receptor as a multifunctional binding protein. Nature. 1987 Sep 24;329(6137):301–307. doi: 10.1038/329301a0. [DOI] [PubMed] [Google Scholar]
  59. Morikawa K., Walker S. M., Nakajima M., Pathak S., Jessup J. M., Fidler I. J. Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice. Cancer Res. 1988 Dec 1;48(23):6863–6871. [PubMed] [Google Scholar]
  60. Murnane M. J., Sheahan K., Ozdemirli M., Shuja S. Stage-specific increases in cathepsin B messenger RNA content in human colorectal carcinoma. Cancer Res. 1991 Feb 15;51(4):1137–1142. [PubMed] [Google Scholar]
  61. Nakajima M., Morikawa K., Fabra A., Bucana C. D., Fidler I. J. Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells. J Natl Cancer Inst. 1990 Dec 19;82(24):1890–1898. doi: 10.1093/jnci/82.24.1890. [DOI] [PubMed] [Google Scholar]
  62. Nicolson G. L. Organ specificity of tumor metastasis: role of preferential adhesion, invasion and growth of malignant cells at specific secondary sites. Cancer Metastasis Rev. 1988 Jun;7(2):143–188. doi: 10.1007/BF00046483. [DOI] [PubMed] [Google Scholar]
  63. Nishimura Y., Kawabata T., Kato K. Identification of latent procathepsins B and L in microsomal lumen: characterization of enzymatic activation and proteolytic processing in vitro. Arch Biochem Biophys. 1988 Feb 15;261(1):64–71. doi: 10.1016/0003-9861(88)90104-x. [DOI] [PubMed] [Google Scholar]
  64. Offerhaus G. J., Giardiello F. M., Bruijn J. A., Stijnen T., Molyvas E. N., Fleuren G. J. The value of immunohistochemistry for collagen IV expression in colorectal carcinomas. Cancer. 1991 Jan 1;67(1):99–105. doi: 10.1002/1097-0142(19910101)67:1<99::aid-cncr2820670119>3.0.co;2-k. [DOI] [PubMed] [Google Scholar]
  65. Ossowski L., Clunie G., Masucci M. T., Blasi F. In vivo paracrine interaction between urokinase and its receptor: effect on tumor cell invasion. J Cell Biol. 1991 Nov;115(4):1107–1112. doi: 10.1083/jcb.115.4.1107. [DOI] [PMC free article] [PubMed] [Google Scholar]
  66. Poste G., Fidler I. J. The pathogenesis of cancer metastasis. Nature. 1980 Jan 10;283(5743):139–146. doi: 10.1038/283139a0. [DOI] [PubMed] [Google Scholar]
  67. Poulsom R., Pignatelli M., Stetler-Stevenson W. G., Liotta L. A., Wright P. A., Jeffery R. E., Longcroft J. M., Rogers L., Stamp G. W. Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia. Am J Pathol. 1992 Aug;141(2):389–396. [PMC free article] [PubMed] [Google Scholar]
  68. Pyke C., Kristensen P., Ralfkiaer E., Grøndahl-Hansen J., Eriksen J., Blasi F., Danø K. Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas. Am J Pathol. 1991 May;138(5):1059–1067. [PMC free article] [PubMed] [Google Scholar]
  69. Reiter L. S., Kruithof E. K., Cajot J. F., Sordat B. The role of the urokinase receptor in extracellular matrix degradation by HT29 human colon carcinoma cells. Int J Cancer. 1993 Feb 1;53(3):444–450. doi: 10.1002/ijc.2910530316. [DOI] [PubMed] [Google Scholar]
  70. Rijnboutt S., Aerts H. M., Geuze H. J., Tager J. M., Strous G. J. Mannose 6-phosphate-independent membrane association of cathepsin D, glucocerebrosidase, and sphingolipid-activating protein in HepG2 cells. J Biol Chem. 1991 Mar 15;266(8):4862–4868. [PubMed] [Google Scholar]
  71. Rochefort H. Cathepsin D in breast cancer. Breast Cancer Res Treat. 1990 Jul;16(1):3–13. doi: 10.1007/BF01806570. [DOI] [PubMed] [Google Scholar]
  72. Schlechte W., Murano G., Boyd D. Examination of the role of the urokinase receptor in human colon cancer mediated laminin degradation. Cancer Res. 1989 Nov 1;49(21):6064–6069. [PubMed] [Google Scholar]
  73. Sheahan K., Shuja S., Murnane M. J. Cysteine protease activities and tumor development in human colorectal carcinoma. Cancer Res. 1989 Jul 15;49(14):3809–3814. [PubMed] [Google Scholar]
  74. Shimokawa K., Inada K. [Advances of immunohistochemistry and its application to histopathology--studies on liver metastasis of colorectal carcinoma--venous basement membrane laminin]. Rinsho Byori. 1990 Feb;38(2):115–123. [PubMed] [Google Scholar]
  75. Shuja S., Sheahan K., Murnane M. J. Cysteine endopeptidase activity levels in normal human tissues, colorectal adenomas and carcinomas. Int J Cancer. 1991 Sep 30;49(3):341–346. doi: 10.1002/ijc.2910490305. [DOI] [PubMed] [Google Scholar]
  76. Sloane B. F., Moin K., Krepela E., Rozhin J. Cathepsin B and its endogenous inhibitors: the role in tumor malignancy. Cancer Metastasis Rev. 1990 Dec;9(4):333–352. doi: 10.1007/BF00049523. [DOI] [PubMed] [Google Scholar]
  77. Sloane B. F., Rozhin J., Hatfield J. S., Crissman J. D., Honn K. V. Plasma membrane-associated cysteine proteinases in human and animal tumors. Exp Cell Biol. 1987;55(4):209–224. doi: 10.1159/000163420. [DOI] [PubMed] [Google Scholar]
  78. Sloane B. F., Rozhin J., Johnson K., Taylor H., Crissman J. D., Honn K. V. Cathepsin B: association with plasma membrane in metastatic tumors. Proc Natl Acad Sci U S A. 1986 Apr;83(8):2483–2487. doi: 10.1073/pnas.83.8.2483. [DOI] [PMC free article] [PubMed] [Google Scholar]
  79. Spyratos F., Maudelonde T., Brouillet J. P., Brunet M., Defrenne A., Andrieu C., Hacene K., Desplaces A., Rouëssé J., Rochefort H. Cathepsin D: an independent prognostic factor for metastasis of breast cancer. Lancet. 1989 Nov 11;2(8672):1115–1118. doi: 10.1016/s0140-6736(89)91487-6. [DOI] [PubMed] [Google Scholar]
  80. Stein M., Zijderhand-Bleekemolen J. E., Geuze H., Hasilik A., von Figura K. Mr 46,000 mannose 6-phosphate specific receptor: its role in targeting of lysosomal enzymes. EMBO J. 1987 Sep;6(9):2677–2681. doi: 10.1002/j.1460-2075.1987.tb02559.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  81. Stephens R. W., Fordham C. J., Doe W. F. Proenzyme to urokinase-type plasminogen activator in human colon cancer: in vitro inhibition by monocyte minactivin after proteolytic activation. Eur J Cancer Clin Oncol. 1987 Feb;23(2):213–222. doi: 10.1016/0277-5379(87)90017-4. [DOI] [PubMed] [Google Scholar]
  82. Stephens R. W., Pöllänen J., Tapiovaara H., Leung K. C., Sim P. S., Salonen E. M., Rønne E., Behrendt N., Danø K., Vaheri A. Activation of pro-urokinase and plasminogen on human sarcoma cells: a proteolytic system with surface-bound reactants. J Cell Biol. 1989 May;108(5):1987–1995. doi: 10.1083/jcb.108.5.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  83. Stetler-Stevenson W. G., Brown P. D., Onisto M., Levy A. T., Liotta L. A. Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues. J Biol Chem. 1990 Aug 15;265(23):13933–13938. [PubMed] [Google Scholar]
  84. Sunitha I., Meighen D. L., Hartman D. P., Thompson E. W., Byers S. W., Avigan M. I. Hepatocyte growth factor stimulates invasion across reconstituted basement membranes by a new human small intestinal cell line. Clin Exp Metastasis. 1994 Mar;12(2):143–154. doi: 10.1007/BF01753981. [DOI] [PubMed] [Google Scholar]
  85. Suzumiya J., Hasui Y., Kohga S., Sumiyoshi A., Hashida S., Ishikawa E. Comparative study of plasminogen activator antigens in colonic carcinomas and adenomas. Int J Cancer. 1988 Oct 15;42(4):627–632. doi: 10.1002/ijc.2910420426. [DOI] [PubMed] [Google Scholar]
  86. Tandon A. K., Clark G. M., Chamness G. C., Chirgwin J. M., McGuire W. L. Cathepsin D and prognosis in breast cancer. N Engl J Med. 1990 Feb 1;322(5):297–302. doi: 10.1056/NEJM199002013220504. [DOI] [PubMed] [Google Scholar]
  87. Thorpe S. M., Rochefort H., Garcia M., Freiss G., Christensen I. J., Khalaf S., Paolucci F., Pau B., Rasmussen B. B., Rose C. Association between high concentrations of Mr 52,000 cathepsin D and poor prognosis in primary human breast cancer. Cancer Res. 1989 Nov 1;49(21):6008–6014. [PubMed] [Google Scholar]
  88. Turnay J., Olmo N., Gavilanes J. G., Lizarbe M. A. Collagen metabolism in human colon adenocarcinoma. Connect Tissue Res. 1989;23(4):251–260. doi: 10.3109/03008208909005625. [DOI] [PubMed] [Google Scholar]
  89. Vachon P. H., Durand J., Beaulieu J. F. Basement membrane formation and re-distribution of the beta 1 integrins in a human intestinal co-culture system. Anat Rec. 1993 Apr;235(4):567–576. doi: 10.1002/ar.1092350409. [DOI] [PubMed] [Google Scholar]
  90. Vignon F., Rochefort H. Interactions of pro-cathepsin D and IGF-II on the mannose-6-phosphate/IGF-II receptor. Breast Cancer Res Treat. 1992;22(1):47–57. doi: 10.1007/BF01833333. [DOI] [PubMed] [Google Scholar]
  91. Vogelstein B., Fearon E. R., Hamilton S. R., Kern S. E., Preisinger A. C., Leppert M., Nakamura Y., White R., Smits A. M., Bos J. L. Genetic alterations during colorectal-tumor development. N Engl J Med. 1988 Sep 1;319(9):525–532. doi: 10.1056/NEJM198809013190901. [DOI] [PubMed] [Google Scholar]
  92. Yamori T., Ota D. M., Cleary K. R., Irimura T. Increased content of chondroitin sulfate proteoglycan in human colorectal carcinoma metastases compared with the primary tumor as determined by an anti-chondroitin-sulfate monoclonal antibody. J Cell Biochem. 1988 Apr;36(4):405–416. doi: 10.1002/jcb.240360409. [DOI] [PubMed] [Google Scholar]
  93. Yoshimoto M., Itoh F., Yamamoto H., Hinoda Y., Imai K., Yachi A. Expression of MMP-7(PUMP-1) mRNA in human colorectal cancers. Int J Cancer. 1993 Jun 19;54(4):614–618. doi: 10.1002/ijc.2910540415. [DOI] [PubMed] [Google Scholar]
  94. van der Stappen J. W., Paraskeva C., Williams A. C., Hague A., Maciewicz R. A. Relationship between the secretion of cysteine proteinases and their inhibitors and malignant potential. Biochem Soc Trans. 1991 Nov;19(4):362S–362S. doi: 10.1042/bst019362s. [DOI] [PubMed] [Google Scholar]

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