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. 1995 May;69(5):3201–3205. doi: 10.1128/jvi.69.5.3201-3205.1995

Bovine papillomavirus E1 protein can, by itself, efficiently drive multiple rounds of DNA synthesis in vitro.

C Bonne-Andrea 1, S Santucci 1, P Clertant 1
PMCID: PMC189025  PMID: 7707551

Abstract

Bovine papillomavirus E1 protein was found to be as efficient as the simian virus 40 large T antigen in initiating DNA synthesis in a cell-free system derived from COS1 cells. Multiple rounds of DNA synthesis occur, initiated at the bovine papillomavirus type 1 origin. Therefore, E1 functions in vitro as a lytic virus initiator.

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Selected References

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