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. 1997 Dec;78(6):572–576. doi: 10.1136/hrt.78.6.572

Comparison of the long term prognostic value of peak exercise oxygen pulse and peak oxygen uptake in patients with chronic heart failure

A Cohen-Solal 1, P Barnier 1, F Pessione 1, P Seknadji 1, D Logeart 1, T Laperche 1, R Gourgon 1
PMCID: PMC1892330  PMID: 9470873

Abstract

Objective—To evaluate the ratio of peak oxygen consumption to peak heart rate (peak oxygen pulse) as a predictor of long term prognosis in chronic heart failure.
Patients and setting—178 consecutive heart failure patients recruited to the cardiology department of a tertiary referral centre between 1986 and 1993. 
Design—Bicycle ergometry with measurement of respiratory exchange. Mean (SD) follow up was 32 (25) months.
Results—Patients who died had a lower peak oxygen consumption (16.0 (5.5) v 18.0 (5.5) ml/min/kg, p = 0.05), lower indexed peak oxygen consumption (52 (14) v 60 (16)%, p = 0.006) but similar peak oxygen pulse (8.4 (2.6) v 8.4 (3.0) ml/beat, NS). The following variables were associated with a good long term prognosis: New York Heart Association class II, non-ischaemic heart failure, peak oxygen consumption ⩾ 17 ml/min/kg, indexed peak oxygen consumption > 63%. Peak oxygen pulse did not have predictive value. Only indexed peak oxygen consumption remained an independent predictor of survival in multivariate analysis.
Conclusions—Peak oxygen pulse has lower prognostic value than peak oxygen consumption, especially when the latter is indexed to predicted values.

 Keywords: prognosis;  oxygen consumption;  oxygen pulse;  exercise;  heart failure

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Figure 1  .

Figure 1  

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Probability of survival according to the baseline indexed peak oxygen consumption (V̇O2), expressed as a percentage of predicted values, greater or lower than 63%. Curves were constructed with the Kaplan-Meier method (p = 0.0003).

Figure 2  .

Figure 2  

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Probability of survival according to baseline peak oxygen pulse (peak O2 pulse). The cut off value was 8.6 ml. Curves were constructed with the Kaplan-Meier method (p = NS).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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