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. 1992 Jan;36(1):209–213. doi: 10.1128/aac.36.1.209

In vitro activities of chloroquine in combination with chlorpromazine or prochlorperazine against isolates of Plasmodium falciparum.

L K Basco 1, J Le Bras 1
PMCID: PMC189259  PMID: 1590691

Abstract

The combinations of chloroquine plus chlorpromazine and chloroquine plus prochlorperazine were evaluated in vitro for potentiation against isolates of Plasmodium falciparum. Potentiation was observed against all chloroquine-resistant isolates. There was no potentiation against 8 of 10 chloroquine-susceptible isolates. The results indicated that the phenothiazines can potentiate chloroquine action against resistant parasites found in natural conditions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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