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Human leukemia engraftment of NOD-SCID mice. Sublethally irradiated mice were injected with 1 × 106 unsorted cells (top row) or 5 × 103 CD34+/CD38--sorted cells (bottom row) from leukemia sample 1 (Tables 1 and 2). After 14 weeks, mice were killed and the bone marrow cells were analyzed for expression of human and murine CD45 (left), and human CD13 and CD33 (right). Total marrow is shown, with no gates applied.
