Table 1.

Summary of hematopathologic characteristics of oncogenic NRAS mice

Experiment	No. of animals	Latency, d*	WBCs, × 103/μL†	Hematocrit, %‡	Spleen weight, g	Liver weight, g
1
HT
CMML	3	36	75-103	25.3 ± 4.6	0.88 ± 0.1	1.59 ± 0.29
AML	5	41	14-40	24 ± 5.3	0.49 ± 0.0	1.2 ± 0.007
LT
CMML	6	62	77-207	31 ± 9.6	1.04 ± 0.6	1.65 ± 0.38
AML	6	57	16-48	27.5 ± 11.6	0.59 ± 0.08	1.47 ± 0.15
2
HT
AML	5	28	22-35	21.6 ± 13.3	0.91 ± 0.3	1.72 ± 0.54
LT
CMML	4	54	79-120	32 ± 5.4	0.7 ± 0.0	1.44 ± 0.23
AML	4	45	13-37	26.3 ± 14.3	0.73 ± 0.08	1.34 ± 0.06
3
HT
AML	6	30	12-55	21.5 ± 11.2	0.71 ± 0.14	1.53 ± 0.37
LT
CMML	2	75	64-141	31.5 ± 0.7	1.02 ± 0.01	2.5 ± 1.54
AML	4	87	16-43	36.3 ± 16.2	0.72 ± 0.5	0.99 ± 0.45

Hematocrit, spleen weight, and liver weight are average ± SD.

HT indicates high-titer retroviruses (∼ 7 × 10⁶-8 × 10⁶ TU/mL); LT, low-titer retroviruses (∼ 6 × 10⁵-7 × 10⁵TU/mL).

^*Latency is the median latency within the particular group.

^†WBC count is given as the range of WBCs for the diseased mice within a particular disease group; values also reflect the SI unit of measure, × 10⁹/L.

^‡Multiply values by 0.01 to obtain SI unit of measure (proportion of 1.0).