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. 1995 Dec;69(12):8169–8172. doi: 10.1128/jvi.69.12.8169-8172.1995

The Epstein-Barr virus nuclear antigen leader protein associates with hsp72/hsc73.

J B Mannick 1, X Tong 1, A Hemnes 1, E Kieff 1
PMCID: PMC189776  PMID: 7494344

Abstract

Epstein-Barr virus nuclear antigen leader protein (EBNA-LP) is important for primary B-lymphocyte growth transformation. We now demonstrate that the W repeat-encoded domain of EBNA-LP significantly associates with proteins of the heat shock protein 70 family (hsp72/hsc73). hsp72/hsc73 may mediate the previously observed interaction between EBNA-LP and the retinoblastoma protein or p53.

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Selected References

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