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. 1984 Mar;114(3):487–495.

Morphologic and biochemical studies of canine mucopolysaccharidosis I.

R M Shull, R G Helman, E Spellacy, G Constantopoulos, R J Munger, E F Neufeld
PMCID: PMC1900418  PMID: 6320652

Abstract

This report presents the necropsy and biochemical findings on the first dog to die with alpha-L-iduronidase deficiency (mucopolysaccharidosis I, MPS I). Gross pathologic features, light- and electron-microscopic findings, and tissue enzyme, glycosaminoglycan (GAG), and sphingolipid levels are compared with the human disease counterpart and the previously described feline model. Results lend further support for the similarities of the canine disease and human MPS I.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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