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. 1996 May;70(5):3325–3329. doi: 10.1128/jvi.70.5.3325-3329.1996

Characterization of long-term cultures of hepatitis C virus.

N Nakajima 1, M Hijikata 1, H Yoshikura 1, Y K Shimizu 1
PMCID: PMC190202  PMID: 8627819

Abstract

The human T- and B-cell lines HPBMa10-2 and Daudi produced infectious hepatitis C virus (HCV) for more than 1 year after infection. The infectivity titer of the cell culture-grown HCV and its genome titer were comparable. The virion density in sucrose was around 1.12 g/ml. Among the 13 variants detected in the inoculum, 7 were adsorbed by the cells and one particular HCV sequence which was present in minor quantities in the inoculum persisted.

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Selected References

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