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. 1980 Nov;101(2):415–424.

The occurrence of fibromuscular dysplasia in the arteries of domestic turkeys.

L M Julian
PMCID: PMC1903604  PMID: 7435545

Abstract

Fibromuscular dysplasia (FMD) was found in 24 of 31 turkeys studied. This is the first species other than man in which FMD has been reported. FMD in turkeys simulates lesions variously known as fibromuscular dysplasia, fibromuscular hyperplasia, and medial hyperplasia in man. It occurred in turkeys from 8 weeks to 1 year of age and was evenly distributed between the sexes (11 males, 13 females). FMD in turkeys is a disease of arterioles and small arteries 44 mu to 666 mu in diameter. A lesion of more than 2.6 mm in length (in an artery 0.1 mm in diameter) was encountered. An adherent thrombus over 670 mu long was seen attached to an FMD lesion. Angiopathy appears to be basic to the pathogenesis of FMD and is characterized by endothelial hyperplasia, smooth-muscle vacuolization, and patchy necrosis of the media.

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Selected References

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  1. Collins G. J., Jr, Rich N. M., Hobson R. W., Andersen C. Fibromuscular dysplasia of the internal carotid arteries. Surgery. 1977 Jan;81(1):105–110. [PubMed] [Google Scholar]
  2. Esterly J. R., Oppenheimer E. H. Vascular lesions in infants with congenital rubella. Circulation. 1967 Oct;36(4):544–554. doi: 10.1161/01.cir.36.4.544. [DOI] [PubMed] [Google Scholar]
  3. Foster J. H., Oates J. A., Rhamy R. K., Klatte E. C., Burko H. C., Michelakis A. M. Hypertension and fibromuscular dysplasia of the renal arteries. Surgery. 1969 Jan;65(1):157–181. [PubMed] [Google Scholar]
  4. Frens D. B., Petajan J. H., Anderson R., Deblanc J. H., Jr Fibromuscular dysplasia of the posterior cerebral artery: report of a case and review of the literature. Stroke. 1974 Mar-Apr;5(2):161–166. doi: 10.1161/01.str.5.2.161. [DOI] [PubMed] [Google Scholar]
  5. HANSON L. J., STROMBERG M. W., KITCHELL R. L., KERNKAMP H. C. Studies on myoclonia congenita. II. Gross and microscopic pathology. Am J Vet Res. 1958 Apr;19(71):383–387. [PubMed] [Google Scholar]
  6. HUNT J. C., HARRISON E. G., Jr, KINCAID O. W., BERNATZ P. E., DAVIS G. D. Idiopathic fibrous and fibromuscular stenoses of the renal arteries associated with hypertension. Proc Staff Meet Mayo Clin. 1962 Mar 28;37:181–216. [PubMed] [Google Scholar]
  7. Mehigan J. T., Stoney R. J. Arterial microemboli and fibromuscular dysplasia of the external iliac arteries. Surgery. 1977 Apr;81(4):484–486. [PubMed] [Google Scholar]
  8. Minick C. R., Fabricant C. G., Fabricant J., Litrenta M. M. Atheroarteriosclerosis induced by infection with a herpesvirus. Am J Pathol. 1979 Sep;96(3):673–706. [PMC free article] [PubMed] [Google Scholar]
  9. PALUBINSKAS A. J., RIPLEY H. R. FIBROMUSCULAR HYPERPLASIA IN EXTRARENAL ARTERIES. Radiology. 1964 Mar;82:451–455. doi: 10.1148/82.3.451. [DOI] [PubMed] [Google Scholar]
  10. Palubinskas A. J., Perloff D., Newton T. H. Fibromuscular hyperplasia, an arterial dysplasia of increasing clinical importance. Am J Roentgenol Radium Ther Nucl Med. 1966 Dec;98(4):907–913. doi: 10.2214/ajr.98.4.907. [DOI] [PubMed] [Google Scholar]
  11. Pfister H. I. On the Distribution of the Elastic Tissue in the Blood Vessels of Birds. J Anat. 1927 Jan;61(Pt 2):213–222.1. [PMC free article] [PubMed] [Google Scholar]
  12. Rothfield N. J. Experimental fibromuscular arterial dysplasia. Radiology. 1969 Dec;93(6):1291–1297. doi: 10.1148/93.6.1291. [DOI] [PubMed] [Google Scholar]
  13. Stanley J. C., Fry W. J., Seeger J. F., Hoffman G. L., Gabrielsen T. O. Extracranial internal carotid and vertebral artery fibrodysplasia. Arch Surg. 1974 Aug;109(2):215–222. doi: 10.1001/archsurg.1974.01360020077015. [DOI] [PubMed] [Google Scholar]
  14. Stanley J. C., Gewertz B. L., Bove E. L., Sottiurai V., Fry W. J. Arterial fibrodysplasia. Histopathologic character and current etiologic concepts. Arch Surg. 1975 May;110(5):561–566. doi: 10.1001/archsurg.1975.01360110107018. [DOI] [PubMed] [Google Scholar]
  15. Stewart D. R., Price R. A., Nebesar R., Schuster S. R. Progressive peripheral fibromuscular hyperplasia in an infant: a possible manifestation of the rubella syndrome. Surgery. 1973 Mar;73(3):374–380. [PubMed] [Google Scholar]
  16. Twigg H. L., Palmisano P. J. Fibromuscular hyperplasia of the iliac artery. A case report. Am J Roentgenol Radium Ther Nucl Med. 1965 Oct;95(2):418–423. doi: 10.2214/ajr.95.2.418. [DOI] [PubMed] [Google Scholar]

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