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. 1980 Dec;101(3):494–511.

Mechanisms of exocytosis in phagocytic inflammatory cells. Parke-Davis Award Lecture.

P M Henson
PMCID: PMC1903647  PMID: 7004205

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ackerman N. R., Beebe J. R. Release of lysosomal enzymes by alveolar mononuclear cells. Nature. 1974 Feb 15;247(5441):475–477. doi: 10.1038/247475a0. [DOI] [PubMed] [Google Scholar]
  2. Axline S. G., Cohn Z. A. In vitro induction of lysosomal enzymes by phagocytosis. J Exp Med. 1970 Jun 1;131(6):1239–1260. doi: 10.1084/jem.131.6.1239. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Becker E. L., Showell H. J., Henson P. M., Hsu L. S. The ability of chemotactic factors to induce lysosomal enzyme release. I. The characteristics of the release, the importance of surfaces and the relation of enzyme release to chemotactic responsiveness. J Immunol. 1974 Jun;112(6):2047–2054. [PubMed] [Google Scholar]
  4. Benveniste J., Henson P. M., Cochrane C. G. Leukocyte-dependent histamine release from rabbit platelets. The role of IgE, basophils, and a platelet-activating factor. J Exp Med. 1972 Dec 1;136(6):1356–1377. doi: 10.1084/jem.136.6.1356. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Berlin R. D., Fera J. P., Pfeiffer J. R. Reversible phagocytosis in rabbit polymorphonuclear leukocytes. J Clin Invest. 1979 Jun;63(6):1137–1144. doi: 10.1172/JCI109407. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Berlin R. D., Oliver J. M. Analogous ultrastructure and surface properties during capping and phagocytosis in leukocytes. J Cell Biol. 1978 Jun;77(3):789–804. doi: 10.1083/jcb.77.3.789. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Caulfield J. P., Lewis R. A., Hein A., Austen K. F. Secretion in dissociated human pulmonary mast cells. Evidence for solubilization of granule contents before discharge. J Cell Biol. 1980 May;85(2):299–312. doi: 10.1083/jcb.85.2.299. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Davies P., Bonney R. J. Secretory products of mononuclear phagocytes: a brief review. J Reticuloendothel Soc. 1979 Jul;26(1):37–47. [PubMed] [Google Scholar]
  9. Dvorak A. M., Hammond M. E., Morgan E., Orenstein N. S., Galli S. J., Dvorak H. F. Evidence for a vesicular transport mechanism in guinea pig basophilic leukocytes. Lab Invest. 1980 Feb;42(2):263–276. [PubMed] [Google Scholar]
  10. Dvorak A. M., Mihm M. C., Jr, Dvorak H. F. Degranulation of basophilic leukocytes in allergic contact dermatitis reactions in man. J Immunol. 1976 Mar;116(3):687–695. [PubMed] [Google Scholar]
  11. Farquhar M. G. Recovery of surface membrane in anterior pituitary cells. Variations in traffic detected with anionic and cationic ferritin. J Cell Biol. 1978 Jun;77(3):R35–R42. doi: 10.1083/jcb.77.3.r35. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Fletcher M. P., Gallin J. I. Degranulating stimuli increase the availability of receptors on human neutrophils for the chemoattractant f-met-leu-phe. J Immunol. 1980 Apr;124(4):1585–1588. [PubMed] [Google Scholar]
  13. Hawkins D. Biopolymer membrane: a model system for the study of the neutrophilic leukocyte response to immune complexes. J Immunol. 1971 Aug;107(2):344–352. [PubMed] [Google Scholar]
  14. Henson P. M., McCarthy K., Larsen G. L., Webster R. O., Giclas P. C., Dreisin R. B., King T. E., Shaw J. O. Complement fragments, alveolar macrophages, and alveolitis. Am J Pathol. 1979 Oct;97(1):93–110. [PMC free article] [PubMed] [Google Scholar]
  15. Henson P. M. Mechanisms of release of granule enzymes from human neutrophils phagocytosing aggregated immunoglobulin. An electron microscopic study. Arthritis Rheum. 1973 Mar-Apr;16(2):208–216. doi: 10.1002/art.1780160211. [DOI] [PubMed] [Google Scholar]
  16. Henson P. M., Oades Z. G. Stimulation of human neutrophils by soluble and insoluble immunoglobulin aggregates. Secretion of granule constituents and increased oxidation of glucose. J Clin Invest. 1975 Oct;56(4):1053–1061. doi: 10.1172/JCI108152. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Henson P. M. The immunologic release of constituents from neutrophil leukocytes. I. The role of antibody and complement on nonphagocytosable surfaces or phagocytosable particles. J Immunol. 1971 Dec;107(6):1535–1546. [PubMed] [Google Scholar]
  18. Henson P. M. The immunologic release of constituents from neutrophil leukocytes. II. Mechanisms of release during phagocytosis, and adherence to nonphagocytosable surfaces. J Immunol. 1971 Dec;107(6):1547–1557. [PubMed] [Google Scholar]
  19. Hoffstein S., Weissmann G. Microfilaments and microtubules in calcium ionophore-induced secretion of lysosomal enzymes from human polymorphonuclear leukocytes. J Cell Biol. 1978 Sep;78(3):769–781. doi: 10.1083/jcb.78.3.769. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Jensen M. S., Bainton D. F. Temporal changes in pH within the phagocytic vacuole of the polymorphonuclear neutrophilic leukocyte. J Cell Biol. 1973 Feb;56(2):379–388. doi: 10.1083/jcb.56.2.379. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Kaplan R. L., Schocket A. L., King T. E., Maulitz R. M., Good J. T., Jr, Stanford R. E., Sahn S. A. A model of immune complex-mediated pleuropulmonary injury; evidence of deposition of circulating immune complexes in the lung. Am J Pathol. 1980 Jul;100(1):115–130. [PMC free article] [PubMed] [Google Scholar]
  22. Larsen G. L., McCarthy K., Webster R. O., Henson J., Henson P. M. A differential effect of C5a and C5a des Arg in the induction of pulmonary inflammation. Am J Pathol. 1980 Jul;100(1):179–192. [PMC free article] [PubMed] [Google Scholar]
  23. Liotta L. A., Tryggvason K., Garbisa S., Hart I., Foltz C. M., Shafie S. Metastatic potential correlates with enzymatic degradation of basement membrane collagen. Nature. 1980 Mar 6;284(5751):67–68. doi: 10.1038/284067a0. [DOI] [PubMed] [Google Scholar]
  24. McCarthy K., Henson P. M. Induction of lysosomal enzyme secretion by alveolar macrophages in response to the purified complement fragments C5a and C5a des-arg. J Immunol. 1979 Dec;123(6):2511–2517. [PubMed] [Google Scholar]
  25. Morrison D. C., Roser J. F., Curry B. J., Henson P. M., Ulevitch R. J. Two distinct mechanisms for the initiation of mast cell degranulation. II. A specific inhibition of amine release by serum proteins. Inflammation. 1978 Mar;3(1):7–25. doi: 10.1007/BF00917318. [DOI] [PubMed] [Google Scholar]
  26. Painter R. G., McIntosh A. T. The regional association of actin and myosin with sites of particle phagocytosis. J Supramol Struct. 1979;12(3):369–384. doi: 10.1002/jss.400120308. [DOI] [PubMed] [Google Scholar]
  27. Pesanti E. L., Axline S. G. Colchicine effects on lysosomal enzyme induction and intracellular degradation in the cultivated macrophage. J Exp Med. 1975 May 1;141(5):1030–1046. doi: 10.1084/jem.141.5.1030. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Schneider Y. J., Tulkens P., de Duve C., Trouet A. Fate of plasma membrane during endocytosis. II. Evidence for recycling (shuttle) of plasma membrane constituents. J Cell Biol. 1979 Aug;82(2):466–474. doi: 10.1083/jcb.82.2.466. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Schnyder J., Baggiolini M. Role of phagocytosis in the activation of macrophages. J Exp Med. 1978 Dec 1;148(6):1449–1457. doi: 10.1084/jem.148.6.1449. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Schnyder J., Baggiolini M. Secretion of lysosomal hydrolases by stimulated and nonstimulated macrophages. J Exp Med. 1978 Aug 1;148(2):435–450. doi: 10.1084/jem.148.2.435. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Segal A. W., Dorling J., Coade S. Kinetics of fusion of the cytoplasmic granules with phagocytic vacuoles in human polymorphonuclear leukocytes. Biochemical and morphological studies. J Cell Biol. 1980 Apr;85(1):42–59. doi: 10.1083/jcb.85.1.42. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Shaw J. O., Henson P. M., Henson J., Webster R. O. Lung inflammation induced by complement-derived chemotactic fragments in the alveolus. Lab Invest. 1980 May;42(5):547–558. [PubMed] [Google Scholar]
  33. Steinman R. M., Brodie S. E., Cohn Z. A. Membrane flow during pinocytosis. A stereologic analysis. J Cell Biol. 1976 Mar;68(3):665–687. doi: 10.1083/jcb.68.3.665. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. Stossel T. P. Contractile proteins in phagocytosis: an example of cell surface-to-cytoplasm communication. Fed Proc. 1977 Jul;36(8):2181–2184. [PubMed] [Google Scholar]
  35. Weissmann G., Zurier R. B., Spieler P. J., Goldstein I. M. Mechanisms of lysosomal enzyme release from leukocytes exposed to immune complexes and other particles. J Exp Med. 1971 Sep 1;134(3 Pt 2):149s–165s. [PubMed] [Google Scholar]

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