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. 1964 Apr;44(4):645–662.

Chronic Alcoholism with Fatty Metamorphosis of the Liver

Mitochondrial Alterations in Hepatic Cells

Donald J Svoboda, Robert T Manning

PMCID: PMC1907028 PMID: 5877511

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

BARGMANN W., KNOOP A. [Vacuole formation and the mitochondria]. Z Zellforsch Mikrosk Anat. 1960;51:456–466. [PubMed] [Google Scholar]
BENNETT H. S., LUFT J. H. zeta-Collidine as a basis for buffering fixatives. J Biophys Biochem Cytol. 1959 Aug;6(1):113–114. doi: 10.1083/jcb.6.1.113. [DOI] [PMC free article] [PubMed] [Google Scholar]
CARRUTHERS J. S., STEINER J. W. Experimental extrahepatic biliary obstruction. Fine structural changes of liver cell mitochondria. Gastroenterology. 1962 Apr;42:419–430. [PubMed] [Google Scholar]
CENTURY B., HORWITT M. K. Effect of dietary lipids upon mitochondrial composition and swelling. J Nutr. 1963 Jun;80:145–150. doi: 10.1093/jn/80.2.145. [DOI] [PubMed] [Google Scholar]
DUNCAN D., HILD W. Mitochondrial alterations in cultures of the central nervous system as observed with the electron microscope. Z Zellforsch Mikrosk Anat. 1960;51:126–137. [PubMed] [Google Scholar]
FAWCETT D. W., ITO S. Observations on the cytoplasmic membranes of testicular cells, examined by phase contrast and electron microscopy. J Biophys Biochem Cytol. 1958 Mar 25;4(2):135–142. doi: 10.1083/jcb.4.2.135. [DOI] [PMC free article] [PubMed] [Google Scholar]
FIGUEROA R. B., KLOTZ A. P. Alterations of alcohol dehydrogenase and other hepatic enzymes following oral alcohol intoxication. Am J Clin Nutr. 1962 Sep;11:235–239. doi: 10.1093/ajcn/11.3.235. [DOI] [PubMed] [Google Scholar]
FIGUEROA R. B., KLOTZ A. P. Alterations of alcohol dehydrogenase and other hepatic enzymes in experimental chronic liver disease. Metabolism. 1962 Nov;11:1169–1180. [PubMed] [Google Scholar]
HRUBAN Z., SPARGO B., SWIFT H., WISSLER R. W., KLEINFELD R. G. Focal cytoplasmic degradation. Am J Pathol. 1963 Jun;42:657–683. [PMC free article] [PubMed] [Google Scholar]
KARNOVSKY M. J. Simple methods for "staining with lead" at high pH in electron microscopy. J Biophys Biochem Cytol. 1961 Dec;11:729–732. doi: 10.1083/jcb.11.3.729. [DOI] [PMC free article] [PubMed] [Google Scholar]
KIESSLING K. H., TILANDER K. The effect of prolonged alcohol treatment on the respiration of liver and brain mitochondria from male and female rats. Exp Cell Res. 1963 May;30:476–480. doi: 10.1016/0014-4827(63)90324-0. [DOI] [PubMed] [Google Scholar]
KLATSKIN G. Alcohol and its relation to liver damage. Gastroenterology. 1961 Nov;41:443–451. [PubMed] [Google Scholar]
LAGUENS R., BIANCHI N. Fine structure of the liver in human idiopathic diabetes mellitus. I. Parenchymal cell mitochondria. Exp Mol Pathol. 1963 Jun;2:203–214. doi: 10.1016/0014-4800(63)90035-2. [DOI] [PubMed] [Google Scholar]
LUFT J. H. Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol. 1961 Feb;9:409–414. doi: 10.1083/jcb.9.2.409. [DOI] [PMC free article] [PubMed] [Google Scholar]
LUFT R., IKKOS D., PALMIERI G., ERNSTER L., AFZELIUS B. A case of severe hypermetabolism of nonthyroid origin with a defect in the maintenance of mitochondrial respiratory control: a correlated clinical, biochemical, and morphological study. J Clin Invest. 1962 Sep;41:1776–1804. doi: 10.1172/JCI104637. [DOI] [PMC free article] [PubMed] [Google Scholar]
NAPOLITANO L., FAWCETT D. The fine structure of brown adipose tissue in the newborn mouse and rat. J Biophys Biochem Cytol. 1958 Nov 25;4(6):685–692. doi: 10.1083/jcb.4.6.685. [DOI] [PMC free article] [PubMed] [Google Scholar]
PAPPAS G. D., BRANDT P. W. Mitochondria. I. Fine structure of the complex patterns in the mitochondria of Pelomyxa carolinensis Wilson (Chaos chaos L.). J Biophys Biochem Cytol. 1959 Aug;6(1):85–90. doi: 10.1083/jcb.6.1.85. [DOI] [PMC free article] [PubMed] [Google Scholar]
SCHAFFNER F., LOEBEL A., WEINER H. A., BARKA T. Hepatocellular cytoplasmic changes in acute alcoholic hepatitis. JAMA. 1963 Feb 2;183:343–346. doi: 10.1001/jama.1963.63700050013013c. [DOI] [PubMed] [Google Scholar]
STOECKENIUS W. An electron microscope study of myelin figures. J Biophys Biochem Cytol. 1959 May 25;5(3):491–500. doi: 10.1083/jcb.5.3.491. [DOI] [PMC free article] [PubMed] [Google Scholar]
THERON J. J., HAWTREY A. O., LIEBENBERG N., SCHIRREN V. The pathogenesis of experimental dietary siderosis of the liver. Am J Pathol. 1963 Jul;43:73–91. [PMC free article] [PubMed] [Google Scholar]
WEISS J. M. Mitochondrial changes induced by potassium and sodium in the duodenal absorptive cell as studied with the electron microscope. J Exp Med. 1955 Dec 1;102(6):783–788. doi: 10.1084/jem.102.6.783. [DOI] [PMC free article] [PubMed] [Google Scholar]

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