Skip to main content
The American Journal of Pathology logoLink to The American Journal of Pathology
. 1966 May;48(5):793–809.

Phenobarbital-induced fine structural changes in rat liver.

P C Burger, P B Herdson
PMCID: PMC1907254  PMID: 5937778

Full text

PDF
793

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BERNHARD W., GAUTIER A., ROUILLER C. La notion de microsomes et le problème de la basophilie cytoplasmique; étude critique et expérimentale. Arch Anat Microsc Morphol Exp. 1954;43(3):236–275. [PubMed] [Google Scholar]
  2. BERNHARD W., ROUILLER C. Microbodies and the problem of mitochondrial regeneration in liver cells. J Biophys Biochem Cytol. 1956 Jul 25;2(4 Suppl):355–360. doi: 10.1083/jcb.2.4.355. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CONNEY A. H., BURNS J. J. Stimulatory effect of foreign compounds on ascorbic acid biosynthesis and on drug-metabolizing enzymes. Nature. 1959 Aug 1;184(Suppl 6):363–364. doi: 10.1038/184363a0. [DOI] [PubMed] [Google Scholar]
  4. COOK L., TONER J. J., FELLOWS E. J. The effect of beta-diethylaminoethyl-diphenylpropylacetate hydrochloride (SKF No. 525-A) on hexobarbital. J Pharmacol Exp Ther. 1954 Jun;111(2):131–141. [PubMed] [Google Scholar]
  5. COOPER J. R., AXELROD J., BRODIE B. B. Inhibitory effects of beta-diethylaminoethyl diphenylpropylacetate on a variety of drug metabolic pathways in vitro. J Pharmacol Exp Ther. 1954 Sep;112(1):55–63. [PubMed] [Google Scholar]
  6. FAWCETT D. W. Observations on the cytology and electron microscopy of hepatic cells. J Natl Cancer Inst. 1955 Apr;15(5 Suppl):1475–1503. [PubMed] [Google Scholar]
  7. FOUTS J. R. Interaction of drugs and hepatic microsomes. Fed Proc. 1962 Nov-Dec;21:1107–1111. [PubMed] [Google Scholar]
  8. HERDSON P. B., GARVIN P. J., JENNINGS R. B. FINE STRUCTURAL CHANGES IN RAT LIVER INDUCED BY PHENOBARBITAL. Lab Invest. 1964 Sep;13:1032–1037. [PubMed] [Google Scholar]
  9. HERDSON P. B., GARVIN P. J., JENNINGS R. B. FINE STRUCTURAL CHANGES PRODUCED IN RAT LIVER BY PARTIAL STARVATION. Am J Pathol. 1964 Aug;45:157–181. [PMC free article] [PubMed] [Google Scholar]
  10. HRUBAN Z., SPARGO B., SWIFT H., WISSLER R. W., KLEINFELD R. G. Focal cytoplasmic degradation. Am J Pathol. 1963 Jun;42:657–683. [PMC free article] [PubMed] [Google Scholar]
  11. Herdson P. B., Kaltenbach J. P. Electron microscope studies on enzyme activity and the isolation of thiohydantoin-induced myelin figures in rat liver. J Cell Biol. 1965 Jun;25(3):485–493. doi: 10.1083/jcb.25.3.485. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Hruban Z., Swift H., Slesers A. Effect of triparanol and diethanolamine on the fine structure of hepatocytes and pancreatic acinar cells. Lab Invest. 1965 Sep;14(9):1652–1672. [PubMed] [Google Scholar]
  13. LUFT J. H. Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol. 1961 Feb;9:409–414. doi: 10.1083/jcb.9.2.409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. MINICK O. T., KENT G., ORFEI E., VOLINI F. I. NON-MEMBRANE ENCLOSED INTRAMITOCHONDRIAL DENSE BODIES. Exp Mol Pathol. 1965 Jun;11:311–319. doi: 10.1016/0014-4800(65)90006-7. [DOI] [PubMed] [Google Scholar]
  15. McKELLAR M. The postnatal growth and mitotic activity of the liver of the albino rat. Am J Anat. 1949 Sep;85(2):263-307, incl 6 pl. doi: 10.1002/aja.1000850205. [DOI] [PubMed] [Google Scholar]
  16. Orrenius S., Ericsson J. L., Ernster L. Phenobarbital-induced synthesis of the microsomal drug-metabolizing enzyme system and its relationship to the proliferation of endoplasmic membranes. A morphological and biochemical study. J Cell Biol. 1965 Jun;25(3):627–639. doi: 10.1083/jcb.25.3.627. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. PALADE G. E., SIEKEVITZ P. Liver microsomes; an integrated morphological and biochemical study. J Biophys Biochem Cytol. 1956 Mar 25;2(2):171–200. doi: 10.1083/jcb.2.2.171. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. PORTER K. R., BRUNI C. An electron microscope study of the early effects of 3'-Me-DAB on rat liver cells. Cancer Res. 1959 Nov;19:997–1009. [PubMed] [Google Scholar]
  19. PORTER K. R. Electron microscopy of basophilic components of cytoplasm. J Histochem Cytochem. 1954 Sep;2(5):346–375. doi: 10.1177/2.5.346. [DOI] [PubMed] [Google Scholar]
  20. REMMER H. Der beschleunigte Abbau von Pharmaka in den Lebermikrosomen unter dem Einfluss von Luminal. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1959;235(4):279–290. [PubMed] [Google Scholar]
  21. REMMER H., MERKER H. J. DRUG-INDUCED CHANGES IN THE LIVER ENDOPLASMIC RETICULUM: ASSOCIATION WITH DRUG-METABOLIZING ENZYMES. Science. 1963 Dec 27;142(3600):1657–1658. doi: 10.1126/science.142.3600.1657. [DOI] [PubMed] [Google Scholar]
  22. REMMER H., MERKER H. J. [Enzyme induction and increase of endoplasmic reticulum in liver cells during phenobarbital (Luminal) therapy]. Klin Wochenschr. 1963 Mar 15;41:276–282. doi: 10.1007/BF01483392. [DOI] [PubMed] [Google Scholar]
  23. SHANK R. E., MORRISON G., CHENG C. H., KARL I., SCHWARTZ R. Cell heterogeneity within the hepatic lobule: quantitative histochemistry. J Histochem Cytochem. 1959 Jul;7(4):237–239. doi: 10.1177/7.4.237. [DOI] [PubMed] [Google Scholar]
  24. TRUMP B. F., SMUCKLER E. A., BENDITT E. P. A method for staining epoxy sections for light microscopy. J Ultrastruct Res. 1961 Aug;5:343–348. doi: 10.1016/s0022-5320(61)80011-7. [DOI] [PubMed] [Google Scholar]
  25. WATSON M. L. Staining of tissue sections for electron microscopy with heavy metals. II. Application of solutions containing lead and barium. J Biophys Biochem Cytol. 1958 Nov 25;4(6):727–730. doi: 10.1083/jcb.4.6.727. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The American Journal of Pathology are provided here courtesy of American Society for Investigative Pathology

RESOURCES