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. 1966 Dec;49(6):1023–1051.

Aflatoxin B1 injury in rat and monkey liver.

D Svoboda, H J Grady, J Higginson
PMCID: PMC1907286  PMID: 4959013

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Selected References

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  1. BUSCH H., BYVOET P., SMETANA K. The nucleolus of the cancer cell: a review. Cancer Res. 1963 Mar;23:313–339. [PubMed] [Google Scholar]
  2. BUTLER W. H., BARNES J. M. TOXIC EFFECTS OF GROUNDNUT MEAL CONTAINING AFLATOXIN TO RATS AND GUINEA-PIGS. Br J Cancer. 1963 Dec;17:699–710. doi: 10.1038/bjc.1963.89. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CHEVREMONT M., CHEVREMONT-COMHAIRE S., FIRKET R. Etude de l'action de la ribonucléase sur des cellules vivantes cultivées in vitro et en particulier de ses effets sur la mitose. Arch Biol (Liege) 1956;67(3-4):635–656. [PubMed] [Google Scholar]
  4. CHIPCHASE M. I., BIRNSTIEL M. L. ON THE NATURE OF NUCLEOLAR RNA. Proc Natl Acad Sci U S A. 1963 Dec;50:1101–1107. doi: 10.1073/pnas.50.6.1101. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. CULVENOR C. C., DANN A. T., DICK A. T. Alkylation as the mechanism by which the hepatotoxic pyrrolizidine alkaloids act on cell nuclei. Nature. 1962 Aug 11;195:570–573. doi: 10.1038/195570a0. [DOI] [PubMed] [Google Scholar]
  6. Clifford J. I., Rees K. R. Aflatoxin: a site of action in the rat liver cell. Nature. 1966 Jan 15;209(5020):312–313. doi: 10.1038/209312a0. [DOI] [PubMed] [Google Scholar]
  7. DICKENS F., JONES H. E. THE CARCINOGENIC ACTION OF AFLATOXIN AFTER ITS SUBCUTANEOUS INJECTION IN THE RAT. Br J Cancer. 1963 Dec;17:691–698. doi: 10.1038/bjc.1963.88. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. EMMELOT P., BENEDETTI E. L. Changes in the fine structure of rat liver cells brought about by dimethylnitrosamine. J Biophys Biochem Cytol. 1960 Apr;7:393–396. doi: 10.1083/jcb.7.2.393. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. FRAYSSINET C., LAFARGE C., DERECONDO A. M., LEBRETON E. INHIBITION DE L'HYPERTROPHIE COMPENSATRICE DU FOIE CHEZ LE RAT PAR LES TOXINES D'ASPERGILLUS FLAVUS. C R Hebd Seances Acad Sci. 1964 Sep 28;259:2143–2146. [PubMed] [Google Scholar]
  10. KRAYBILL H. F., SHIMKIN M. B. CARCINOGENESIS RELATED TO FOODS CONTAMINATED BY PROCESSING AND FUNGAL METABOLITES. Adv Cancer Res. 1964;8:191–248. doi: 10.1016/s0065-230x(08)60509-6. [DOI] [PubMed] [Google Scholar]
  11. KURODA Y., FURUYAMA J. Physiological and biochemical studies of effects of mitomycin C on strain HeLa cells in cell culture. Cancer Res. 1963 Jun;23:682–687. [PubMed] [Google Scholar]
  12. LAPIS K., BERNHARD W. THE EFFECT OF MITOMYCIN-C ON THE NUCLEOLAR FINE STRUCTURE OF KB CELLS IN CELL CULTURE. Cancer Res. 1965 Jun;25:628–645. [PubMed] [Google Scholar]
  13. LIAU M. C., HNILICA L. S., HURLBERT R. B. REGULATION OF RNA SYNTHESIS IN ISOLATED NUCLEOLI BY HISTONES AND NUCLEOLAR PROTEINS. Proc Natl Acad Sci U S A. 1965 Mar;53:626–632. doi: 10.1073/pnas.53.3.626. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Lombardi B. Considerations on the pathogenesis of fatty liver. Lab Invest. 1966 Jan;15(1 Pt 1):1–20. [PubMed] [Google Scholar]
  15. MAGEE P. N., FARBER E. Toxic liver injury and carcinogenesis. Methylation of rat-liver nucleic acids by dimethylnitrosamine in vivo. Biochem J. 1962 Apr;83:114–124. doi: 10.1042/bj0830114. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. MONTGOMERY P. O., KARNEY D., REYNOLDS R. C., MCCLENDON D. CELLULAR AND SUBCELLULAR EFFECTS OF IONIZING RADIATIONS. Am J Pathol. 1964 May;44:727–746. [PMC free article] [PubMed] [Google Scholar]
  17. Madhavan T. V., Rao K. S., Tulpule P. G. Effect of dietary protein level on susceptibility of monkeys to aflatoxin liver injury. Indian J Med Res. 1965 Oct;53(10):984–989. [PubMed] [Google Scholar]
  18. OETTLE A. G. CANCER IN AFRICA, ESPECIALLY IN REGIONS SOUTH OF THE SAHARA. J Natl Cancer Inst. 1964 Sep;33:383–439. [PubMed] [Google Scholar]
  19. REYNOLDS R. C., MONTGOMERY P. O., KARNEY D. H. Nucleolars "caps'--a morphologic entity produced by the carcinogen 4-nitroquinoline N-oxide. Cancer Res. 1963 May;23:535–538. [PubMed] [Google Scholar]
  20. Rosenkranz H. S., Lambek C. In vivo effect of nalidixic acid (NegGram) on the DNA of human diploid cells in tissue culture. Proc Soc Exp Biol Med. 1965 Nov;120(2):549–552. doi: 10.3181/00379727-120-30586. [DOI] [PubMed] [Google Scholar]
  21. SCHOEFL G. I. THE EFFECT OF ACTINOMYCIN D ON THE FINE STRUCTURE OF THE NUCLEOLUS. J Ultrastruct Res. 1964 Apr;10:224–243. doi: 10.1016/s0022-5320(64)80007-1. [DOI] [PubMed] [Google Scholar]
  22. SCHOENTAL R. Liver changes and primary liver tumours in rats given toxic guinea pig diet (M.R.C. Diet 18). Br J Cancer. 1961 Dec;15:812–815. doi: 10.1038/bjc.1961.92. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. SCHWARTZ H. S., STERNBERG S. S., PHILIPS F. S. PHARMACOLOGY OF MITOMYCIN C. IV. EFFECTS IN VIVO ON NUCLEIC ACID SYNTHESIS; COMPARISON WITH ACTINOMYCIN D. Cancer Res. 1963 Sep;23:1125–1136. [PubMed] [Google Scholar]
  24. SEIFTER S., DAYTON S. The estimation of glycogen with the anthrone reagent. Arch Biochem. 1950 Jan;25(1):191–200. [PubMed] [Google Scholar]
  25. SMITH R. H., McKERNAN W. Hepatotoxic action of chromatographically separated fractions of Aspergillus flavus extracts. Nature. 1962 Sep 29;195:1301–1303. doi: 10.1038/1951301a0. [DOI] [PubMed] [Google Scholar]
  26. SVOBODA D., HIGGINSON J. ULTRASTRUCTURAL CHANGES PRODUCED BY PROTEIN AND RELATED DEFICIENCIES IN THE RAT LIVER. Am J Pathol. 1964 Sep;45:353–379. [PMC free article] [PubMed] [Google Scholar]
  27. Svoboda D., Soga J. Early effects of pyrrolizidine alkaloids on the fine structure of rat liver cells. Am J Pathol. 1966 Mar;48(3):347–373. [PMC free article] [PubMed] [Google Scholar]
  28. TULPULE P. G., MADHAVAN T. V., GOPALAN C. EFFECT OF FEEDING AFLATOXIN TO YOUNG MONKEYS. Lancet. 1964 May 2;1(7340):962–963. doi: 10.1016/s0140-6736(64)91748-9. [DOI] [PubMed] [Google Scholar]
  29. Theron J. J. Acute liver injury in ducklings as a result of aflatoxin poisoning. Lab Invest. 1965 Sep;14(9):1586–1603. [PubMed] [Google Scholar]
  30. Widnell C. C., Tata J. R. A procedure for the isolation of enzymically active rat-liver nuclei. Biochem J. 1964 Aug;92(2):313–317. doi: 10.1042/bj0920313. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. de IONGH, BEERTHUIS R. K., VLES R. O., BARRETT C. B., ORD W. O. Investigation of the factor in groundnut meal responsible for "turkey X disease". Biochim Biophys Acta. 1962 Dec 17;65:548–551. [PubMed] [Google Scholar]

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