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. 1996 Nov;70(11):8160–8164. doi: 10.1128/jvi.70.11.8160-8164.1996

The reovirus nonstructural protein sigma1NS is recognized by murine cytotoxic T lymphocytes.

L M Hoffman 1, K T Hogan 1, L W Cashdollar 1
PMCID: PMC190895  PMID: 8892946

Abstract

The cytotoxic T-lymphocyte (CTL) response in reovirus-infected C3H mice was investigated by using reovirus-vaccinia virus recombinants. Results of cytotoxicity assays indicated that the nonstructural protein sigma1NS elicited a significant CTL response. Experiments with sigma1NS-specific CTL lines showed that both strain-specific and cross-reactive epitopes exist in the sigma1NS protein.

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Selected References

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