Abstract
The reverse transcription/polymerase chain reaction was used to demonstrate beta 3-adrenoceptor mRNA in rat brain regions. Levels were highest in hippocampus, cerebral cortex and striatum and lower in hypothalamus, brainstem and cerebellum.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Arch J. R., Kaumann A. J. Beta 3 and atypical beta-adrenoceptors. Med Res Rev. 1993 Nov;13(6):663–729. doi: 10.1002/med.2610130604. [DOI] [PubMed] [Google Scholar]
- Berkowitz D. E., Nardone N. A., Smiley R. M., Price D. T., Kreutter D. K., Fremeau R. T., Schwinn D. A. Distribution of beta 3-adrenoceptor mRNA in human tissues. Eur J Pharmacol. 1995 Apr 28;289(2):223–228. doi: 10.1016/0922-4106(95)90098-5. [DOI] [PubMed] [Google Scholar]
- Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987 Apr;162(1):156–159. doi: 10.1006/abio.1987.9999. [DOI] [PubMed] [Google Scholar]
- Cook K. S., Min H. Y., Johnson D., Chaplinsky R. J., Flier J. S., Hunt C. R., Spiegelman B. M. Adipsin: a circulating serine protease homolog secreted by adipose tissue and sciatic nerve. Science. 1987 Jul 24;237(4813):402–405. doi: 10.1126/science.3299705. [DOI] [PubMed] [Google Scholar]
- Glowinski J., Iversen L. L. Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. J Neurochem. 1966 Aug;13(8):655–669. doi: 10.1111/j.1471-4159.1966.tb09873.x. [DOI] [PubMed] [Google Scholar]
- Nicholas A. P., Pieribone V. A., Hökfelt T. Cellular localization of messenger RNA for beta-1 and beta-2 adrenergic receptors in rat brain: an in situ hybridization study. Neuroscience. 1993 Oct;56(4):1023–1039. doi: 10.1016/0306-4522(93)90148-9. [DOI] [PubMed] [Google Scholar]
- Rodriguez M., Carillon C., Coquerel A., Le Fur G., Ferrara P., Caput D., Shire D. Evidence for the presence of beta 3-adrenergic receptor mRNA in the human brain. Brain Res Mol Brain Res. 1995 Apr;29(2):369–375. doi: 10.1016/0169-328x(94)00274-i. [DOI] [PubMed] [Google Scholar]
- Simiand J., Keane P. E., Guitard J., Langlois X., Gonalons N., Martin P., Bianchetti A., Le Fur G., Soubrié P. Antidepressant profile in rodents of SR 58611A, a new selective agonist for atypical beta-adrenoceptors. Eur J Pharmacol. 1992 Aug 25;219(2):193–201. doi: 10.1016/0014-2999(92)90296-g. [DOI] [PubMed] [Google Scholar]