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. 1968 Nov 23;4(5629):487–489. doi: 10.1136/bmj.4.5629.487

Comparison of the Adrenocorticotrophic Activities of Two Synthetic Polypeptides: Synacthen and DW 75*

W W Downie, K Whaley, Mary A Wright, Margaret A Bell, Anne K Taylor
PMCID: PMC1912728  PMID: 4301534

Abstract

The adrenocorticotrophic activities of two synthetic polypeptides, Synacthen (Ciba) and DW 75 (Sandoz), were compared in two groups of patients having a variety of arthritic disorders. Compared with Synacthen, injected either intramuscularly or intravenously, intravenous DW 75 was found to have a longer duration of adrenocorticotrophic activity (measured by plasma 11-hydroxycorticosteroid levels) in both groups of patients, while intramuscularly administered DW 75 did not appear to be absorbed well.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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