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editorial
. 1996 Nov;59(5):983–989.

The TDT and other family-based tests for linkage disequilibrium and association.

R S Spielman, W J Ewens
PMCID: PMC1914831  PMID: 8900224

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cox N. J., Baker L., Spielman R. S. Insulin-gene sharing in sib pairs with insulin-dependent diabetes mellitus: no evidence for linkage. Am J Hum Genet. 1988 Jan;42(1):167–172. [PMC free article] [PubMed] [Google Scholar]
  2. Curtis D., Sham P. C. A note on the application of the transmission disequilibrium test when a parent is missing. Am J Hum Genet. 1995 Mar;56(3):811–812. [PMC free article] [PubMed] [Google Scholar]
  3. Duffy D. L. Screening a 2 cM genetic map for allelic association: a simulated oligogenic trait. Genet Epidemiol. 1995;12(6):595–600. doi: 10.1002/gepi.1370120612. [DOI] [PubMed] [Google Scholar]
  4. Ewens W. J., Spielman R. S. The transmission/disequilibrium test: history, subdivision, and admixture. Am J Hum Genet. 1995 Aug;57(2):455–464. [PMC free article] [PubMed] [Google Scholar]
  5. Falk C. T., Rubinstein P. Haplotype relative risks: an easy reliable way to construct a proper control sample for risk calculations. Ann Hum Genet. 1987 Jul;51(Pt 3):227–233. doi: 10.1111/j.1469-1809.1987.tb00875.x. [DOI] [PubMed] [Google Scholar]
  6. Field L. L., Fothergill-Payne C., Bertrams J., Baur M. P. HLA-DR effects in a large German IDDM dataset. Genet Epidemiol Suppl. 1986;1:323–328. doi: 10.1002/gepi.1370030749. [DOI] [PubMed] [Google Scholar]
  7. Harley J. B., Moser K. L., Neas B. R. Logistic transmission modeling of simulated data. Genet Epidemiol. 1995;12(6):607–612. doi: 10.1002/gepi.1370120614. [DOI] [PubMed] [Google Scholar]
  8. Lander E. S., Schork N. J. Genetic dissection of complex traits. Science. 1994 Sep 30;265(5181):2037–2048. doi: 10.1126/science.8091226. [DOI] [PubMed] [Google Scholar]
  9. Lander E., Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet. 1995 Nov;11(3):241–247. doi: 10.1038/ng1195-241. [DOI] [PubMed] [Google Scholar]
  10. Ott J. Statistical properties of the haplotype relative risk. Genet Epidemiol. 1989;6(1):127–130. doi: 10.1002/gepi.1370060124. [DOI] [PubMed] [Google Scholar]
  11. Parsian A., Todd R. D., Devor E. J., O'Malley K. L., Suarez B. K., Reich T., Cloninger C. R. Alcoholism and alleles of the human D2 dopamine receptor locus. Studies of association and linkage. Arch Gen Psychiatry. 1991 Jul;48(7):655–663. doi: 10.1001/archpsyc.1991.01810310073013. [DOI] [PubMed] [Google Scholar]
  12. Rice J. P., Neuman R. J., Hoshaw S. L., Daw E. W., Gu C. TDT with covariates and genomic screens with mod scores: their behavior on simulated data. Genet Epidemiol. 1995;12(6):659–664. doi: 10.1002/gepi.1370120623. [DOI] [PubMed] [Google Scholar]
  13. Schaid D. J., Sommer S. S. Comparison of statistics for candidate-gene association studies using cases and parents. Am J Hum Genet. 1994 Aug;55(2):402–409. [PMC free article] [PubMed] [Google Scholar]
  14. Sham P. C., Curtis D. An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Ann Hum Genet. 1995 Jul;59(Pt 3):323–336. doi: 10.1111/j.1469-1809.1995.tb00751.x. [DOI] [PubMed] [Google Scholar]
  15. Spielman R. S., Baur M. P., Clerget-Darpoux F. Genetic analysis of IDDM: summary of GAW5 IDDM results. Genet Epidemiol. 1989;6(1):43–58. doi: 10.1002/gepi.1370060111. [DOI] [PubMed] [Google Scholar]
  16. Spielman R. S., McGinnis R. E., Ewens W. J. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet. 1993 Mar;52(3):506–516. [PMC free article] [PubMed] [Google Scholar]
  17. Terwilliger J. D. A powerful likelihood method for the analysis of linkage disequilibrium between trait loci and one or more polymorphic marker loci. Am J Hum Genet. 1995 Mar;56(3):777–787. [PMC free article] [PubMed] [Google Scholar]
  18. Thomson G. Mapping disease genes: family-based association studies. Am J Hum Genet. 1995 Aug;57(2):487–498. [PMC free article] [PubMed] [Google Scholar]
  19. Thomson G., Robinson W. P., Kuhner M. K., Joe S., Klitz W. HLA and insulin gene associations with IDDM. Genet Epidemiol. 1989;6(1):155–160. doi: 10.1002/gepi.1370060129. [DOI] [PubMed] [Google Scholar]

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