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. 1997 May;71(5):4145–4149. doi: 10.1128/jvi.71.5.4145-4149.1997

The poly(C) region affects progression of encephalomyocarditis virus infection in Langerhans' islets but not in the myocardium.

A Zimmermann 1, A Botta 1, G Arnold 1, H J Eggers 1, B Nelsen-Salz 1
PMCID: PMC191573  PMID: 9094698

Abstract

The diabetogenic variant PV2 of encephalomyocarditis virus was cloned, and three recombinants differing in their 5' poly(C) tracts were analyzed. It is shown that the poly(C) region is not essential for infectivity in mice but does influence the virus load and degree of pathological lesions within the Langerhans' islets but not in the myocardium.

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Selected References

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