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. 1963 Jan 5;88(1):19–22.

Congenital Hypofibrinogenemia in Five Members of a Family

R Hasselback, Rita B Marion, J W Thomas
PMCID: PMC1920904  PMID: 13960907

Abstract

The bleeding tendency in five members of one family with fibrinogen levels ranging from 58 mg. % to 158 mg. % was mild and chiefly related to dental extractions. Abruptio placentae in one patient produced severe bleeding. Reports of menstrual bleeding patterns in patients with defects of hemostatic mechanisms suggest that normal platelets, vascular function and extrinsic and possibly intrinsic coagulation systems, except for fibrinogen, control menstrual blood loss. An autosomal dominant gene with variable penetrance may determine fibrinogen levels.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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