Abstract
Of a series of 122 children suffering from acute purulent meningitis at the Children's Hospital, Winnipeg, in the years 1952-56, 12 (9.8%) succumbed, all deaths occurring in those 12 months of age or less. Fortyone of the survivors were re-studied 2.5 to 7.5 years after their acute illness to assess the nature and incidence of sequelae, the relationship of sequelae to the severity of the acute illness, and the correlation between the various methods of identifying sequelae. Five children exhibited psychiatric evidence of organic brain damage; seven, neurological abnormality; 11, electroencephalographic abnormality. Three had defective intelligence and nine psychological test evidence of organic brain damage. Children with sequelae tended to have several abnormal test results, the total number with neuropsychiatric and/or psychological sequelae being 11 (26%). There was a positive correlation between the severity of the acute illness and the presence of neuropsychiatric sequelae; also between neuropsychiatric sequelae, defective intelligence and psychological evidence of brain damage. No correlation existed between the electroencephalographic abnormality and neuropsychiatric defect.
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Selected References
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- BLOOR B. M., GRANT R. S., TABRIS J. A. Sequelae of meningitis due to Hemophilus influenza, an analysis of 44 cases. J Am Med Assoc. 1950 Jan 28;142(4):241–243. doi: 10.1001/jama.1950.02910220021005. [DOI] [PubMed] [Google Scholar]
- CROOK W. G., CLANTON B. R., HODES H. L. Hemophilus influenzae meningitis; observations on the treatment of 110 cases. Pediatrics. 1949 Nov;4(5):643–659. [PubMed] [Google Scholar]
- GROVE W. E., FOX M. J. Postmeningitic complications with particular reference to otologic sequelae. Ann Otol Rhinol Laryngol. 1949 Sep;58(3):771–788. doi: 10.1177/000348944905800314. [DOI] [PubMed] [Google Scholar]
- HESTETUN S. Seinfølger av Hemophilusinfluenzaemeningitis; en analyse av 32 tilfelle. Nord Med. 1951 Jun 20;45(25):965–968. [PubMed] [Google Scholar]
- HUGHES J. G., DAVIS B. C., CARPENTER A. E. Relationship of EEG findings to clinical factors during and after acute purulent meningitis. AMA Am J Dis Child. 1951 Sep;82(3):268–281. doi: 10.1001/archpedi.1951.02040040282002. [DOI] [PubMed] [Google Scholar]
- Pai M. N. Changes in Personality after Cerebrospinal Fever. Br Med J. 1945 Mar 3;1(4391):289–293. doi: 10.1136/bmj.1.4391.289. [DOI] [PMC free article] [PubMed] [Google Scholar]
- TURRELL R. C., ROSEMAN E. Electro encephalographic studies of the encephalopathies. IV. Serial studies in meningococcic meningitis. AMA Arch Neurol Psychiatry. 1955 Feb;73(2):141–148. [PubMed] [Google Scholar]