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. 1963 Sep 7;89(10):503–507.

Reticulum Cell Sarcoma of the Central Nervous System

K Sorger
PMCID: PMC1921886  PMID: 14042802

Abstract

One variety of sarcoma of the central nervous system (CNS) has been referred to under such synonyms as perithelial sarcoma, microglioma, and reticulum cell sarcoma. A case of diffuse involvement of the CNS is reported and the author believes that the tumour is a reticulum cell sarcoma because: (1) in addition to involvement of the CNS, lesions characteristic of a diffuse lymphomatous process were present in extraneural sites; (2) silver carbonate impregnation of the tumour cells was demonstrated. This tinctorial property has been reported as characteristic of microgliomas but has been shown to be an unreliable criterion for the differentiation of the cells of microglial from those of reticulum cell sarcomas. It is concluded that in such cases the CNS is the initial and major focus of a multicentric malignant lymphoma which has the histologic characteristics of a reticulum cell sarcoma.

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Selected References

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  1. FISHER E. R., DAVIS E. R., LEMMEN L. J. Reticulum-cell sarcoma of brain (microglioma). AMA Arch Neurol Psychiatry. 1959 May;81(5):591–598. doi: 10.1001/archneurpsyc.1959.02340170057004. [DOI] [PubMed] [Google Scholar]
  2. HANBERY J. W., DUGGER G. S. Perithelial sarcoma of the brain; a clinicopathological study of thirteen cases. AMA Arch Neurol Psychiatry. 1954 Jun;71(6):732–761. doi: 10.1001/archneurpsyc.1954.02320420060007. [DOI] [PubMed] [Google Scholar]
  3. NICHOLS P., Jr, WAGNER J. A. Primary intracranial sarcoma; report of nine cases with suggested classification. J Neuropathol Exp Neurol. 1952 Jul;11(3):215–234. doi: 10.1097/00005072-195207000-00001. [DOI] [PubMed] [Google Scholar]
  4. TROLAND C. E., SAHYOUN P. F., MANDEVILLE F. B. Primary mesenchymal tumors of the brain, so-called reticulum cell sarcoma; report of 5 cases. J Neuropathol Exp Neurol. 1950 Jul;9(3):322–334. doi: 10.1097/00005072-195007000-00006. [DOI] [PubMed] [Google Scholar]
  5. WILKE G. Uber primäre Reticuloendotheliosen des Gehirns, mit besonderer Berücksichtigung bisher unbekannter eigenartiger granulomatöser Hirnprozesse. Dtsch Z Nervenheilkd. 1950;164(4):332–380. [PubMed] [Google Scholar]

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