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. 1962 Jul 21;2(5298):149–151.
Inefficiency of Purified Diphtheria Formol Toxoid in Primary Immunization Against Diphtheria
A Report to the Medical Research Council by its Committee on Diphtheria Toxoid*
*
Members of the Committee.—Professor D. G. Evans (chairman), Miss Mollie Barr, Dr. W. C. Cockburn, Dr. L. B. Holt, Dr. D. A. Long, Dr. A. Shaw, and Dr. J. Ungar.
Preparation of toxoid.—The diphtheria formol toxoid was prepared by Dr. L. B. Holt at the Wright-Fleming Institute of Microbiology.
Laboratory tests for antigenic potency.—The toxoid was tested for potency by Miss M. Barr, Professor D. G. Evans, Dr. L. B. Holt, and Dr. J. Ungar.
Titration of Sera.—The children's sera were titrated for antitoxin by Miss M. Barr at the Wellcome Research Laboratories.
Trials in children.—The scheme for the immunization and follow-up of the children was prepared by Dr. W. C. Cockburn and carried out by Professor D. B. Bradshaw, Dr. A. Shaw, and Mrs. D. Holliday, of the Public Health Department, Leeds.
Professor D. G. Evans and Dr. L. B. Holt prepared the report.
PMCID: PMC1925358 PMID: 20789460