Skip to main content
PMC home page
Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1971 Oct 23;105(8):819–825.

The measles epidemic in Calgary 1969-70: the protective effect of vaccination for the individual and the community

Agnes Eagles O'Neil
PMCID: PMC1931212  PMID: 5170695

Abstract

Twenty per cent of the city's population of 375,000 had had live measles vaccination as pre-school children in the preceding four years. Protection rates for killed-live vaccine schedule (Edmonston) and live vaccine only (Schwarz) were approximately 66%, not diminishing in four years; the rates for killed vaccine only (three doses) were similar for 18 months, diminishing later. As the numbers who have acquired immunity by contracting the disease fall by 10 percentage points, numbers immunized by live vaccines must rise by 15 percentage points to maintain an equivalent balance of immune and susceptible subjects.

Full text

PDF
819

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADAMS J. M., IMAGAWA D. T., WRIGHT S. W., TARJAN G. Measles immunization with live avian distemper virus. Virology. 1959 Mar;7(3):351–353. doi: 10.1016/0042-6822(59)90205-3. [DOI] [PubMed] [Google Scholar]
  2. Baratta R. O., Ginter M. C., Price M. A., Walker J. W., Skinner R. G., Prather E. C., David J. K. Measles (rubeola) in previously immunized children. Pediatrics. 1970 Sep;46(3):397–402. [PubMed] [Google Scholar]
  3. Buser F. Side reaction to measles vaccination suggesting the Arthus phenomenon. N Engl J Med. 1967 Aug 3;277(5):250–251. doi: 10.1056/NEJM196708032770507. [DOI] [PubMed] [Google Scholar]
  4. Dull H. B., Witte J. J. Progress of measles eradication in the United States. Public Health Rep. 1968 Mar;83(3):245–248. [PMC free article] [PubMed] [Google Scholar]
  5. Fulginiti V. A., Eller J. J., Downie A. W., Kempe C. H. Altered reactivity to measles virus. Atypical measles in children previously immunized with inactivated measles virus vaccines. JAMA. 1967 Dec 18;202(12):1075–1080. doi: 10.1001/jama.202.12.1075. [DOI] [PubMed] [Google Scholar]
  6. Gokiert J. G., Beamish W. E. Altered reactivity to measles virus in previously vaccinated children. Can Med Assoc J. 1970 Oct 10;103(7):724–727. [PMC free article] [PubMed] [Google Scholar]
  7. Jean-Joseph P., Sow S., Casey H. L., Imperato P. J., Henderson R. H., Noble J., Jr A comparison of Edmonston-B and Schwarz measles vaccine in Malian children. Lancet. 1969 Mar 29;1(7596):665–667. doi: 10.1016/s0140-6736(69)92025-x. [DOI] [PubMed] [Google Scholar]
  8. KRUGMAN S., GILES J. P., JACOBS A. M., FRIEDMAN H. Studies with live attenuated measles-virus vaccine. Comparative clinical, antigenic, and prophylactic effects after inoculation with and without gamma-globulin. Am J Dis Child. 1962 Mar;103:353–363. [PubMed] [Google Scholar]
  9. Levitt L. P., Case G. E., Neil J. S., Casey H. L., Adler P., Ferreri S., Witte J. J. Determination of measles immunity after a mass immunization campaign. Public Health Rep. 1970 Mar;85(3):261–265. [PMC free article] [PubMed] [Google Scholar]
  10. Macmorine H. G., Parisius W. Purification and concentration of formaldehyde inactivated measles vaccine by an adsorption-elution procedure. Can J Public Health. 1968 Nov;59(11):441–448. [PubMed] [Google Scholar]
  11. PARTINGTON M. W., QUINTON J. F. The pre-eruptive illness of measles. Arch Dis Child. 1959 Apr;34(174):149–153. doi: 10.1136/adc.34.174.149. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Schaffner W., Schluederberg A. E., Byrne E. B. Clinical epidemiology of sporadic measles in a highly immunized population. N Engl J Med. 1968 Oct 10;279(15):783–789. doi: 10.1056/NEJM196810102791501. [DOI] [PubMed] [Google Scholar]
  13. Scott T. F., Bonanno D. E. Reactions to live-measles-virus vaccine in children previously inoculated with killed-virus vaccine. N Engl J Med. 1967 Aug 3;277(5):248–250. doi: 10.1056/NEJM196708032770506. [DOI] [PubMed] [Google Scholar]
  14. Sutherland I., Fayers P. M. Effect of measles vaccination on incidence of measles in the community. Br Med J. 1971 Mar 27;1(5751):698–702. doi: 10.1136/bmj.1.5751.698. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Wilson S., Weber J. C., Aprile M. A., Macmorine H. G. Detection of sensitizing tissue culture components in viral vaccines. J Allergy. 1968 Dec;42(6):319–329. doi: 10.1016/0021-8707(68)90094-4. [DOI] [PubMed] [Google Scholar]

Articles from Canadian Medical Association Journal are provided here courtesy of Canadian Medical Association

RESOURCES