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. 1959 Aug;35(4):819–833.

The Removal of Cartilage Matrix in Vivo by Papain

Prevention of Recovery with Cortisone, Hydrocortisone and Prednisolone*

Robert T McCluskey, Lewis Thomas
PMCID: PMC1934832  PMID: 13670314

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CLARK I., UMBREIT W. W. Effect of cortisone and other steroids upon in vitro synthesis of chondroitin sulfate. Proc Soc Exp Biol Med. 1954 Jul;86(3):558–561. doi: 10.3181/00379727-86-21164. [DOI] [PubMed] [Google Scholar]
  2. DZIEWIATKOWSKI D. D. Radioautographic visualization of sulfur-35 disposition in the articular cartilage and bone of suckling rats following injection of labeled sodium sulfate. J Exp Med. 1951 May;93(5):451–458. doi: 10.1084/jem.93.5.451. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. FOLLIS R. H., Jr Effect of cortisone on growing bones of the rat. Proc Soc Exp Biol Med. 1951 Apr;76(4):722–724. doi: 10.3181/00379727-76-18607. [DOI] [PubMed] [Google Scholar]
  4. McCLUSKEY R. T., THOMAS L. The removal of cartilage matrix, in vivo, by papain; identification of crystalline papain protease as the cause of the phenomenon. J Exp Med. 1958 Sep 1;108(3):371–384. doi: 10.1084/jem.108.3.371. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. SCHILLER S., DORFMAN A. The metabolism of mucopolysaccharides in animals: the effect of cortisone and hydrocortisone on rat skin. Endocrinology. 1957 Mar;60(3):376–381. doi: 10.1210/endo-60-3-376. [DOI] [PubMed] [Google Scholar]
  6. SCHILLER S., MATHEWS M. B., CIFONELLI J. A., DORFMAN A. The metabolism of mucopolysaccharides in animals. III. Further studies on skin utilizing C14-glucose, C14-acetate, and S35-sodium sulfate. J Biol Chem. 1956 Jan;218(1):139–145. [PubMed] [Google Scholar]
  7. SPICER S. S., BRYANT J. H. Cartilage changes in papain-treated rabbits. Am J Pathol. 1957 Nov-Dec;33(6):1237–1245. [PMC free article] [PubMed] [Google Scholar]
  8. THOMAS L. Reversible collapse of rabbit ears after intravenous papain, and prevention of recovery by cortisone. J Exp Med. 1956 Aug 1;104(2):245–252. doi: 10.1084/jem.104.2.245. [DOI] [PMC free article] [PubMed] [Google Scholar]

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