Abstract
A pilot study was undertaken for a diabetes detection program based upon quantitative microanalysis for glucose of postprandial finger-tip blood from subjects attending a tuberculosis preventive survey. A glucose level of over 120 mg./100 ml. was regarded as a positive screen test. Fifty of the 967 subjects in the pilot study had positive tests. Ten of these were excluded from follow-up because of age and a borderline screen test, and eight refused follow-up or could not be traced. Glucose tolerance tests on the remaining subjects who “screened” positive indicated that 1% of the original number had had false-positive screen tests, while 1% were diabetic and 0.5% were possibly diabetic. These data indicate that this screening method is sufficiently sensitive to detect most of the individuals with undiagnosed diabetes in the population, without picking up an undue number of subjects who have slight abnormalities of glucose metabolism without known clinical significance.
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Selected References
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- CONN J. W., FAJANS S. S. The prediabetic state. A concept of dynamic resistance to a genetic diabetogenic influence. Am J Med. 1961 Dec;31:839–850. doi: 10.1016/0002-9343(61)90023-7. [DOI] [PubMed] [Google Scholar]
- ENTMACHER P. S., MARKS H. H. DIABETES IN 1964; A WORLD SURVEY. Diabetes. 1965 Apr;14:212–223. doi: 10.2337/diab.14.4.212. [DOI] [PubMed] [Google Scholar]
- FAJANS S. S., CONN J. W. The early recognition of diabetes mellitus. Ann N Y Acad Sci. 1959 Sep 25;82:208–218. doi: 10.1111/j.1749-6632.1959.tb44901.x. [DOI] [PubMed] [Google Scholar]
- GOTTFRIED S. P., PELZ K. S., CLIFFORD R. C. Carbohydrate metabolism in healthy old men and women over 70 years of age. Am J Med Sci. 1961 Oct;242:475–480. doi: 10.1097/00000441-196110000-00013. [DOI] [PubMed] [Google Scholar]
- HARKNESS J. Prevalence of glycosuria and diabetes mellitus. A comprehensive survey in an urban community. Br Med J. 1962 Jun 2;1(5291):1503–1507. doi: 10.1136/bmj.1.5291.1503. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HARTING D., GLENN B. A comparison of blood-sugar and urine-sugar determinations for the detection of diabetes. N Engl J Med. 1951 Jul 12;245(2):48–54. doi: 10.1056/NEJM195107122450202. [DOI] [PubMed] [Google Scholar]
- HOZIER J. B., EDERMA A. B. ADMINISTRATION OF A DIABETES-SCREENING PROGRAM FOR FEDERAL EMPLOYEES. Ind Med Surg. 1964 Jan;33:22–24. [PubMed] [Google Scholar]
- KENT G. T., LEONARDS J. R. MASS SCREENING FOR DIABETES IN A METROPOLITAN AREA USING FINGER BLOOD GLUCOSE AFTER A CARBOHYDRATE LOAD. Diabetes. 1965 May;14:295–299. doi: 10.2337/diab.14.5.295. [DOI] [PubMed] [Google Scholar]
- KNOWLES H. C., Jr, GUEST G. M., LAMPE J., KESSLER M., SKILLMAN T. G. THE COURSE OF JUVENILE DIABETES TREATED WITH UNMEASURED DIET. Diabetes. 1965 May;14:239–273. doi: 10.2337/diab.14.5.239. [DOI] [PubMed] [Google Scholar]
- Keen H. Diabetes Survey in Bedford 1962. Proc R Soc Med. 1964 Mar;57(3):200–202. doi: 10.1177/003591576405700321. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MCDONALD G. W., FISHER G. F., BURNHAM C. REPRODUCIBILITY OF THE ORAL GLUCOSE TOLERANCE TEST. Diabetes. 1965 Aug;14:473–480. doi: 10.2337/diab.14.8.473. [DOI] [PubMed] [Google Scholar]
- MUNKE A. A MASS SURVEY TO TRACE PREVIOUSLY UNKNOWN DIABETES MELLITUS. A PRELIMINARY REPORT. Acta Med Scand. 1964 Aug;176:169–179. doi: 10.1111/j.0954-6820.1964.tb00923.x. [DOI] [PubMed] [Google Scholar]
- PACKER H., HAWKES J. M., ACKERMAN R. F. A comparison of urine and blood tests in diabetes detection. Diabetes. 1961 Jul-Aug;10:280–285. doi: 10.2337/diab.10.4.280. [DOI] [PubMed] [Google Scholar]
- Spaulding W. B., Spitzer W. O., Truscott P. W. Aglycosuric Diabetes. Can Med Assoc J. 1963 Aug 24;89(8):329–333. [PMC free article] [PubMed] [Google Scholar]
- TATON J., POMETTA D., CAMERINI-DAVALOS R. A., MARBLE A. GENETIC DETERMINISM TO DIABETES AND TOLERANCE TO GLUCOSE. Lancet. 1964 Dec 26;2(7374):1360–1362. doi: 10.1016/s0140-6736(64)91156-0. [DOI] [PubMed] [Google Scholar]
- WEST K. M., WULFF J. A., REIGEL D. G., FITZGERALD D. T. ORAL CARBOHYDRATE TOLERANCE TESTS. Arch Intern Med. 1964 May;113:641–648. doi: 10.1001/archinte.1964.00280110021004. [DOI] [PubMed] [Google Scholar]
