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Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1967 Jan 21;96(3):153–157.

Immunization Against Rabies

R S McWilliam, J L Penistan
PMCID: PMC1935942  PMID: 6066820

Abstract

The methods used for both pre-exposure and post-exposure immunization against rabies were studied. In pre-exposure immunization duck embryo vaccine should be used. In post-exposure immunization either duck embryo or Semple-type vaccine appears to be effective in stimulating antibody production. Both vaccines may cause neurological sequelae. A dose of vaccine should be given 20-50 days after completion of the primary course of vaccination. Immune serum should be used in all severe exposures especially of the head and neck, and in individuals in whom the commencement of vaccination has been unduly delayed. In individuals who have been previously vaccinated reinforcing doses have been found to be effective even as long as 20 years after the primary vaccination. A tissue culture vaccine has been developed and is about to undergo field trials.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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