Abstract
In 72 pregnant women with culture-proved vaginal candidiasis, and an equal number of controls matched for parity, size, stage of gestation and age, the intravenous glucose tolerance curves were compared using Silverstone's method. The results in both study and control groups did not differ and resembled closely those in Silverstone's series. Half the study group were treated using nystatin alone, while the other half also received tolbutamide. The cure rate was equal in the two groups. Candidiasis in pregnancy does not appear to be related to altered glucose metabolism nor does the addition of this hypoglycemic drug (tolbutamide) improve results. No ill effects, fetal or maternal, were apparent following the use of tolbutamide.
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Selected References
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- LUNDBAEK K. Intravenous glucose tolerance as a tool in definition and diagnosis of diabetes mellitus. Br Med J. 1962 Jun 2;1(5291):1507–1513. doi: 10.1136/bmj.1.5291.1507. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SILVERSTONE F. A., SOLOMONS E., RUBRICIUS J. The rapid intravenous glucose tolerance test in pregnancy. J Clin Invest. 1961 Dec;40:2180–2189. doi: 10.1172/JCI104444. [DOI] [PMC free article] [PubMed] [Google Scholar]