Abstract
A retrospective study was done in children in whom salmonellosis was confirmed by laboratory findings with the aim of reviewing etiology, epidemiology, clinical manifestations and therapy. The 15 serotypes most frequently isolated from stool, and in exceptional cases from urine, are discussed. If patients with typhoid fever are excluded, only one patient (who subsequently died) had a blood culture positive for Salmonella, specifically S. enteritidis.
No seasonal or other peaks of incidence were noted. Age appeared to be important; of 81 patients with gastroenteritis, 30 were less than 6 months old.
Two children in the older age group developed complications; one with appendicitis required surgery.
Ten strains of Salmonella out of 23 tested by the disc method showed in vitro resistance to ampicillin on primary isolation.
Acquired in vitro resistance to one or more antibiotics appeared to develop with six Salmonella strains reisolated from patients after or during antibiotic treatment.
In several children the stool cultures remained positive after clinical signs had disappeared. These findings strongly suggest that, even though antibiotic therapy may improve the symptoms of Salmonella infection, it does not decrease the number of carriers during the convalescent period.
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Selected References
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- ADINARAYANAN N., FOLTZ V. D., MCKINLEY F. INCIDENCE OF SALMONELLAE IN PREPARED AND PACKAGED FOODS. J Infect Dis. 1965 Feb;115:19–26. doi: 10.1093/infdis/115.1.19. [DOI] [PubMed] [Google Scholar]
- CLYDE W. A., Jr Salmonellosis in infants and children; a study of 100 cases. Pediatrics. 1957 Feb;19(2):175–183. [PubMed] [Google Scholar]
- COHEN R. A., GERACI J. E., DEARING W. H., NEEDHAM G. M. SALMONELLOSIS: OBSERVATIONS ON 94 PATIENTS. Mayo Clin Proc. 1964 Jun;39:401–409. [PubMed] [Google Scholar]
- MACCREADY R. A., REARDON J. P., SAPHRA I. Salmonellosis in Massachusetts; a sixteen-year experience. N Engl J Med. 1957 Jun 13;256(24):1121–1128. doi: 10.1056/NEJM195706132562401. [DOI] [PubMed] [Google Scholar]
- ROSENSTEIN B. J., RUSSO P., HINCHLIFFE M. C. A FAMILY OUTBREAK OF SALMONELLOSIS TRACED TO A PET TURTLE. N Engl J Med. 1965 May 6;272:960–961. doi: 10.1056/NEJM196505062721807. [DOI] [PubMed] [Google Scholar]
- SLEET R. A., SANGSTER G., MURDOCH J. M. COMPARISON OF AMPICILLIN AND CHLORAMPHENICOL IN TREATMENT OF PARATYPHOID FEVER. Br Med J. 1964 Jan 18;1(5376):148–150. doi: 10.1136/bmj.1.5376.148. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WATANABE T., FUKASAWA T. Episome-mediated transfer of drug resistance in Enterobacteriaceae. I. Transfer of resistance factors by conjugation. J Bacteriol. 1961 May;81:669–678. doi: 10.1128/jb.81.5.669-678.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]
- WATANABE T. Infective heredity of multiple drug resistance in bacteria. Bacteriol Rev. 1963 Mar;27:87–115. doi: 10.1128/br.27.1.87-115.1963. [DOI] [PMC free article] [PubMed] [Google Scholar]
- YURACK J. A., BEST E. W. SALMONELLA CONTROL IN CANADA. Can J Public Health. 1964 Feb;55:47–54. [PubMed] [Google Scholar]
- YURACK J. A. RESISTANCE OF SALMONELLAE ISOLATED IN 1962 TO TETRACYCLINE, CHLORAMPHENICOL, AND AMPICILLIN. Can J Microbiol. 1964 Aug;10:521–526. doi: 10.1139/m64-065. [DOI] [PubMed] [Google Scholar]