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. 1972 Oct 7;107(7):626–631.

Cholestyramine and medium-chain triglyceride in prolonged management of patients subjected to ileal resection or bypass

C Noel Williams, Robert C Dickson
PMCID: PMC1940965  PMID: 4665095

Abstract

The pathophysiology of cholerrheic enteropathy is described and a series of patients reviewed. Of 11 patients with chronic disabling diarrhea and steatorrhea after ileal resection or bypass, two had recurrent ileitis, three had lactose intolerance and six of those operated on five years or more previously had vitamin B12 deficiency. Cholestyramine was given alone or with medium-chain triglyceride (MCT) or Portagen (MCT and lactose). The maximal response occurred when cholestyramine was given with Portagen — significantly reduced stool frequency and weight in all patients and stool fat in five. Restudy of five patients four to 11 months later showed the same pattern of response: cholestyramine with 70% MCT abolished symptoms in four patients (ileectomy) and 100% MCT alone greatly improved the condition of the fifth (extensive small bowel resection).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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