Abstract
Two unrelated Chinese-Canadian families with recurrent hydrops fetalis are described. The investigation, acid-base and blood gas studies, and clinical course of one hydropic fetus with large amounts of hemoglobin Bart's who survived for three hours are described. Data for the parents of both families, consistent with the alphathalassemia carrier state, are presented.
Full text
PDF




Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Gray G. R., Marion R. B. Thalassemia and G-6-PD deficiency in Chinese-Canadians: admission screening of a hospital population. Can Med Assoc J. 1971 Aug 7;105(3):283–286. [PMC free article] [PubMed] [Google Scholar]
- HORTON B. F., THOMPSON R. B., DOZY A. M., NECHTMAN C. M., NICHOLS E., HUISMAN T. H. Inhomogeneity of hemoglobin. VI. The minor hemoglobin components of cord blood. Blood. 1962 Sep;20:302–314. [PubMed] [Google Scholar]
- JAMES L. S. The effect of pain relief for labor and delivery on the fetus and newborn. Anesthesiology. 1960 Jul-Aug;21:405–430. doi: 10.1097/00000542-196007000-00012. [DOI] [PubMed] [Google Scholar]
- Kan Y. W., Allen A., Lowenstein L. Hydrops fetalis with alpha thalassemia. N Engl J Med. 1967 Jan 5;276(1):18–23. doi: 10.1056/NEJM196701052760103. [DOI] [PubMed] [Google Scholar]
- LIE-INJO L. E. Hydrops foetails and abnormal haemoglobins. J Obstet Gynaecol Br Emp. 1962 Apr;69:288–292. [PubMed] [Google Scholar]
- Lehmann H. Different types of alpha-thalassaemia and significance of haemoglobin Bart's in neonates. Lancet. 1970 Jul 11;1(7663):78–80. doi: 10.1016/s0140-6736(70)92645-0. [DOI] [PubMed] [Google Scholar]
- Pootrakul S., Wasi P., Na-Nakorn S. Haemoglobin Bart's hydrops foetalis in Thailand. Ann Hum Genet. 1967 May;30(4):293–311. doi: 10.1111/j.1469-1809.1967.tb00031.x. [DOI] [PubMed] [Google Scholar]
- Thumasathit B., Nondasuta A., Silpisornkosol S., Lousuebsakul B., Unchalipongse P., Mangkornkanok M. Hydrops fetalis associated with Bart's hemoglobin in northern Thailand. J Pediatr. 1968 Jul;73(1):132–138. doi: 10.1016/s0022-3476(68)80052-6. [DOI] [PubMed] [Google Scholar]
- Todd D., Lai M., Braga C. A. Thalassaemia and hydrops foetalis-family studies. Br Med J. 1967 Aug 5;3(5561):347–349. doi: 10.1136/bmj.3.5561.347. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wasi P., Na-Nakorn S., Pootrakul S., Sookanek M., Disthasongchan P., Panich V., Pornpatkul M. Alpha- and beta-thalassemia in Thailand. Ann N Y Acad Sci. 1969 Nov 20;165(1):60–82. doi: 10.1111/j.1749-6632.1969.tb27777.x. [DOI] [PubMed] [Google Scholar]
- Weatherall D. J., Clegg J. B., Boon W. H. The haemoglobin constitution of infants with the haemoglobin Bart's hydrops foetalis syndrome. Br J Haematol. 1970 Mar;18(3):357–367. doi: 10.1111/j.1365-2141.1970.tb01449.x. [DOI] [PubMed] [Google Scholar]





