Abstract
Clindamycin, by intravenous or intramuscular administration, was used in the treatment of 18 patients seriously ill with infections due to bacteroides organisms. In 17 cases there was a rapid favourable clinical response to treatment. No serious toxic effects were observed. This study appears to confirm previous in vitro evidence that clindamycin is presently the antibiotic of choice for such infections.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Geddes A. M., Bridgwater F. A., Williams D. N., Oon J., Grimshaw G. J. Clinical and bacteriological studies with clindamycin. Br Med J. 1970 Jun 20;2(5711):703–704. doi: 10.1136/bmj.2.5711.703. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ingham H. R., Selkon J. B., Codd A. A., Hale J. H. A study in vitro of the sensitivity to antibiotics of Bacteroides fragilis. J Clin Pathol. 1968 Jul;21(4):432–436. doi: 10.1136/jcp.21.4.432. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ingham H. R., Selkon J. B., Codd A. A., Hale J. H. The effect of carbon dioxide on the sensitivity of Bacteroides fragilis to certain antibiotics in vitro. J Clin Pathol. 1970 Apr;23(3):254–258. doi: 10.1136/jcp.23.3.254. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kagnoff M. F., Armstrong D., Blevins A. Bacteroides bacteremia. Experience in a hospital for neoplastic diseases. Cancer. 1972 Jan;29(1):245–251. doi: 10.1002/1097-0142(197201)29:1<245::aid-cncr2820290137>3.0.co;2-v. [DOI] [PubMed] [Google Scholar]
- Kislak J. W. The susceptibility of Bacteroides fragilis to 24 antibiotics. J Infect Dis. 1972 Mar;125(3):295–299. doi: 10.1093/infdis/125.3.295. [DOI] [PubMed] [Google Scholar]
- Martin W. J., Gardner M., Washington J. A., 2nd In vitro antimicrobial susceptibility of anaerobic bacteria isolated from clinical specimens. Antimicrob Agents Chemother. 1972 Feb;1(2):148–158. doi: 10.1128/aac.1.2.148. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nastro L. J., Finegold S. M. Bactericidal activity of five antimicrobial agents against Bacteroides fragilis. J Infect Dis. 1972 Jul;126(1):104–107. doi: 10.1093/infdis/126.1.104. [DOI] [PubMed] [Google Scholar]
- Tillotson J. R., Lerner A. M. Bacteroides pneumonias. Characteristics of cases with empyema. Ann Intern Med. 1968 Feb;68(2):308–317. doi: 10.7326/0003-4819-68-2-308. [DOI] [PubMed] [Google Scholar]
- Tracy O., Gordon A. M., Moran F., Love W. C., McKenzie P. Lincomycins in the treatment of bacteroides infections. Br Med J. 1972 Jan 29;1(5795):280–282. doi: 10.1136/bmj.1.5795.280. [DOI] [PMC free article] [PubMed] [Google Scholar]