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. Author manuscript; available in PMC: 2007 Aug 13.
Published in final edited form as: Bone. 2006 Sep 25;40(2):316–322. doi: 10.1016/j.bone.2006.08.004

Fig. 5.

Fig. 5

Anti-ICAM-1 inhibits ECF-L-induced OCL formation, treated by 10−10 M 1,25-(OH)2D3 and/or ECF-L-Fc (200 ng/ml). Anti-ICAM-1 antibody was added to mouse bone marrow cultures stimulated with 200 ng/ml of ECF-L-Fc and/or 10−10 M 1,25-(OH)2D3. Control cultures were treated with a control Fc protein (200 ng/ml) and control IgG protein. Anti-ICAM-1 antibody did not inhibit TRACP+ MNC induced by 10−10 M 1,25-(OH)2D3, but inhibited TRACP+ MNC formation induced by 10−10 M 1,25-(OH)2D3 and ECF-L-Fc. Results represent the mean±SD. A similar pattern of results was seen in three independent experiments. Open bars represent cultures not treated with ECF-L and solid bars represent cultures treated with ECF-L.