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. 1970 May 9;102(9):943–945.

Variations in Paper Electrophoretic Serum Lipoprotein Patterns in Healthy Subjects

G C Buckley, J A Little, A Csima
PMCID: PMC1946740  PMID: 5538493

Abstract

The normal variations in the paper electrophoretic lipoprotein patterns in 240 healthy Canadian males and females, aged 10 to 59 years, have been described and compared with serum cholesterol and triglyceride levels.

The incidence of abnormal chylomicra, beta and pre-beta lipoproteins was similar in both sexes and increased with age in both sexes.

Chylomicron bands and/or pre-beta trails from the origin occurred in 4% of subjects, pre-beta bands in 27% and “abnormally” dense beta bands in 28%.

Five per cent of subjects were considered to have definite hyperlipoproteinemia, another 19% had slight and 21% had questionable hyperlipoproteinemia. Fifty-five per cent were normal.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADLERSBERG D., SCHAEFER L. E., STEINBERG A. G., WANG C. I. Age, sex, serum lipids, and coronary atherosclerosis. J Am Med Assoc. 1956 Oct 13;162(7):619–622. doi: 10.1001/jama.1956.02970240001001. [DOI] [PubMed] [Google Scholar]
  2. Allard C., Goulet C. Serum lipids: an epidemiological study of an active Montreal population. Can Med Assoc J. 1968 Mar 30;98(13):627–637. [PMC free article] [PubMed] [Google Scholar]
  3. Brown D. F., Doyle J. T. Pre-beta lipoproteinemia. Its bearing on the dietary management of serum lipid disorders as related to ischemic heart disease. Am J Clin Nutr. 1967 Apr;20(4):324–332. doi: 10.1093/ajcn/20.4.324. [DOI] [PubMed] [Google Scholar]
  4. Buckley G. C., Cutler J. M., Little J. A. Serum triglyceride: method of estimation and levels in normal humans. Can Med Assoc J. 1966 Apr 23;94(17):886–888. [PMC free article] [PubMed] [Google Scholar]
  5. CARR J. J., DREKTER I. J. Simplified rapid technic for the extraction and determination of serum cholesterol without saponification. Clin Chem. 1956 Oct;2(5):353–368. [PubMed] [Google Scholar]
  6. Fredrickson D. S., Levy R. I., Lees R. S. Fat transport in lipoproteins--an integrated approach to mechanisms and disorders. N Engl J Med. 1967 Jan 26;276(4):215–contd. doi: 10.1056/NEJM196701262760406. [DOI] [PubMed] [Google Scholar]
  7. Fredrickson D. S., Levy R. I., Lindgren F. T. A comparison of heritable abnormal lipoprotein patterns as defined by two different techniques. J Clin Invest. 1969 Nov;47(11):2446–2457. doi: 10.1172/JCI105927. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. KEYS A., MICKELSEN O., MILLER E. O., HAYES E. R., TODD R. L. The concentration of cholesterol in the blood serum of normal man and its relation to age. J Clin Invest. 1950 Oct;29(10):1347–1353. doi: 10.1172/JCI102372. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. LEES R. S., HATCH F. T. Sharper separation of lipoprotein species by paper electrophoresis in albumin-containing buffer. J Lab Clin Med. 1963 Mar;61:518–528. [PubMed] [Google Scholar]
  10. LITTLE J. A., VAN DER FLIER R. W., SHANOFF H. M. Serum lipids and lipoproteins in healthy adult Canadian males. Can Med Assoc J. 1962 Jun 9;86:1045–1055. [PMC free article] [PubMed] [Google Scholar]

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